Biomolecules & Therapeutics
- 제6권4호
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- Pages.364-370
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- 1998
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- 1976-9148(pISSN)
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- 2005-4483(eISSN)
잠뇨로부터 질소함유 당물질 분리 및 glycosidase에 대한 저해활성
Isolation of N-Containing Sugars from Silkworm Urine and Their Glycosidase Inhibitory Activities
초록
Glycosidase inhibitors from urine of Bombyx mori were isolated and their inhibitory activities on glycosidases were evaluated. Six compounds were isolated by using several ion exchange columns, and their chemical structures were identified by the physicochemical and spectral data. Compound IV, V and Ⅵ were identified as 1-deoxynojirimycin, fagomine and 1,4-dideoxy-1,4-imino-D-arabinitol, respectively. Among six compounds isolated,1-deoxynojirimycin(IV) was the most potent inhibitor on
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