Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
권호 표지

Taurine Level in Human Milk and Estimated Intake of Taurine by Breast -Fed Infants during the Early Period of Lactation

수유 초기 모유 중 타우린 함량과 영아의 섭취량 추정

  • 김을상 (단국대학교 식품영양학과)
  • Published : 1998.04.01
Download PDF
⟨ Previous Next ⟩

Abstract

Taurine is only supplied to the infants from the breast-fed or formula milks because the enzyme activities of taurine biosynthesis are limited in early stages of infants . The objectives of present study were to quantitate the contents of tarurine in human milk and to estimate the intake of taurine by breast-fed infants during early period of lactation. Thirty -three lactating women, volunteered and delivered in R hospital in Serou. were recruited. Milk samples were collected every day at B1-B5 day(from 1 to 5 day dafter start of milk secretion), 15th and 30th day postpartum. Taurine contents were determined by HPLC equipped with RF-detector. The intake of taurine by infants was estimated by multiplization with the infant milk intake reported in our laboratory. The content of taurine was 406$\pm$174nmol/ml at B1-B5 day, and then gradually decreased to 359$\pm$125nmol/ml at 15th day and to 304$\pm$94nmol/ml at 30th day postpartum. The estimated intake of taurine was almost same as 24-25mg/day at B1-B5 day, and 15th , 30th days postpartum . This results was due to the increase of the intake of milk by infants.

Keywords

References

  1. Prev. Med. v.18 Taurine : an overview of its role in preventive medicine Kendler,B.S.
  2. Biochemistry of Sulfur Huxtable,R.J.
  3. J. Neurochem v.17 Free amino acids in the pineal and pituitary glands of human brain Vellan,E.J.;Gjessing,L.R.;Stalsberg,H.
  4. Br. J. Pharmacol. v.52 Transport of taurine by normal human blood platelet Ahtee,L.;Boullin,D.J.;Paasonen,M.K.
  5. Annu. Rev. Biochem. v.55 Taurine : biological update Wright,C.E.;Tallan,H.H.;Lin,Y.Y.;Gaull,G.E.
  6. Physiol. Rev. v.48 Biochemistry and physiology of taurine and taurine derivatives Jacobson,J.G.;Smith,L.H.Jr.
  7. Brain Res. v.41 Free amino acids of chicken and rat retina Pasantes-Morales,H.;Klethi,J.;Ledig,M.;Mandel,P.
  8. Am. J. Clin. Nutr. v.35 Deficiencies of essential and conditionally essential nutrients Chipponi,J.X.;Bleier,J.C.;Santi,M.T.;Rudman,D.
  9. Life Sci. v.26 Taurine : a role in osmotic regulation of mammalian brain and possible clinical significance Thurston,J.H.;Hautart,R.E.;Dirgo,J.A.
  10. Sulfar Amino Acids : Biochemical and Clinical Aspects Taurine in human lymphoblastoid cells : uptake and role in proliferation Gaull,E.;Wright,C.E.;Tallan,H.H.;Kuriyama,K.(ed.);Huxtable,R.J.(ed.);Iwata,H.(ed.)
  11. J. Pharmacol. Exp.Ther. v.232 Taurine modulation of calcium binding to cardiac sarcolemma Sebring,L.A.;Huxtable,R.J.
  12. Biochem. Pharmacol. v.33 Hypoglycemic properties of taurine: not mediated by enhanced insulin release Kulakowski,E.C.;Maturo,J.
  13. Acta Physiol. Pharmacol. Latinoamer. v.35 On the role of taurine in the cerebellar cortex : a reappraisal Bernardi,N.
  14. Xenobiotica v.13 The utilization of exogenous taurine for the conjugation of xenobiotic acids in the ferret Emudianughe,T.S.;Caldwell,J.;Smith,R.L.
  15. Biochem. Pharmacol. v.34 Taurine protection of lymphoblastoid cells from iron-ascorbate induced damage Pasantes-Morales,H.;Wright,C.E.;Gaull,G.E.
  16. Invest. Ophthalmol. v.12 Absolute levels of some free amino acids in normal biologically tractinated retinas Cohen,A.I.;McDaniel,M.;Orr,H.
  17. Modern nutrition in health and disease(7th ed.) Vitamin-like molecules Hayes,K.C.;Shils,M.E.(ed.);Young,V.R.(ed.)
  18. Ann. Rev. Nutr. v.1 Taurine in metabolism Hayes,K.C.;Sturman,J.A.;Darby,W.J.(ed.);Broquist,H.P.(ed.);Olson,R.E.(ed.)
  19. Advances in nutritional research v.3 The biology of taurine in nutrition and development Sturman,J.A.;Hayes,K.C.;Draper,H.H.(ed.)
  20. N. Engl. J. Med. v.312 Nutritional requirement for taurine in patients receiving long-term parenteral nutrition Geggel,H.S.;Ament,M.E.;Heckenlively,J.R.;Martin,D.A.;Kopple,J.D.
  21. Nutrition : Proteins and amino acids Nutrition and metabolism of sulfur amino acids Yamaguchi,K.;Yoshida,A.(ed.);Naito,H(ed.);Niiyama,Y.(ed.);Suguki,T.(ed.)
  22. Ann. Rev. Nutr. v.3 The placenta in nutrition Munro,H.N.;Pilistine,S.J.;Fant,M.E.;Darby,W.J.(ed.);Broquist,H.P.(ed.);Olson,R.E.(ed.)
  23. J. Nutr. v.118 Taurine : Is it reqiured for infant nutrition? Chesney,R.W.
  24. Korean J. Nutrition v.26 no.8 Longitudinal study on taurine intake of breast-fed infants from Korean non-vegetarian and lacto-ovo-vegetarian Kim,E.S.;Lee,J.S.;Choi,K.S.;Cho,K.H.;Seol,M.Y.;Park,M.A.;Lee,K.H.
  25. Korean J. Nutrition v.22 no.1 Longitudinal Changes of the taurine content in the human milk of Korean lacto-ovo-vegetarian Choi,K.S.;Kim,E.S.
  26. Adv. Exp. Med. Biol. v.403 Taurine intake of Korean breast-fed infants during lactation Eul-Sang Kim;Kum-Ho Cho;Mee-Ah Park;Kyu-Han Lee;Jean Moon;Young-Nam Lee;Hee-Kyung Ro
  27. J. Liq. Chromatogr. v.17 no.2 HPLC analysis of taurine in human plasma sample using the DABS-Cl reagent with sensitivity at picomole level Stocchi,V.;Palma,F.;Piccoli,G.;Biagiarelli,B.;Cucchiarini,L.;Magnani,M.
  28. Fed. proc. v.25 Distribution of amino acids between plasma and red blood cells in the dog Elwyn,D.H.
  29. Early Hum. Dev. v.2 Taurine and other amino acid in milk of man other mammals Rassin,D.K.;Sturman,J.A.;Gaull,G.E.
  30. Euro. J. Clin. Nutr. v.43 Effect of suckling and diurnal influences on the concentrations of taurine and other free amino acid in milk Shubat,P.J.;Parker,D.;Huxtable,R.J.
  31. Eur. J. Ped. v.142 Determination of taurine in milk and infant formula diets Erbersdobler,H.F.;Trautwein,E.;Greulich,H.G.
  32. Achi. Med. Res. v.26 Taurine content in breast milk of Mexical women from urban and rural areas Pasantes-Morales,H.;Lopez,I.;Ysunza,A.
  33. Am. J. Clin. Nutr. v.40 Human milk nonprotein nitrogen components : changing pattern of free amino acid and urea in the course of early lactation Harzer,G.;Franzke,V.;Bindels,J.G.
  34. Am. J. Clin. Nutr. v.30 Breast milk composition in Ethiopian and Swedish mother. III. Amino acids and other nitrogenous substances Svanberg,U.I.F.;Gebre-Medhin,M.;Ljungqvist,B.;Olsson,M.
  35. Sulfur Amino Acids v.6 The post-notal changes of trace nutrients in human breast milk Sato,H.;Tada,H.;Yanagida,M.;Yamaguchi,K.
  36. Am. J. Clin. Nutr. v.50 Free amino acid in preterm milk from mothers delivering appropriate or small for gestational age infants Pamblanco,M;Portoles,M.;Paredes,C.;Ten,A.;Comin,J.
  37. Life Science v.35 Changes in maternal taurine in response to pregnancy and lactation Stipanuk,M.H.;Kuo,S.M.;Hirachberger,L.L.
  38. Korean J. Nutrition v.26 no.4 A longitudinal study on human milk intake in exclusively breast-fed infants Seol,M.Y.;Kim,E.S.;Keum,H.K.
  39. Korean J. Nutrition v.28 no.7 Milk, sodium and potassium intakes of breastfed infants during lactation Cho,K.H.;Moon,J.;Keum,H.K.;Kim,E.S.
  40. Korean J. Nutrition v.30 no.5 Changes on breast milk intake and weight of breast-fed infants during the lactation Lee,J.S.;Lee,Y.N.;Kim,E.S.
  41. Korean J. Nutrition v.27 no.6 Changes in transitional milk intakes and body weight of breast-fed infants Lee,J.S.;Kim,E.S.;Kim,B.N.
  42. J. Pediatr. v.90 Milk protein quantity and quality in low birth weight infants. III. Effects on sulfur-containing amino acids in plasma and urine Gaull,G.E.;Rassin,D.K.;Raiha,N.C.R.;Heinonen,K.
  43. Pediatr. Gastroenterol. Nutr. v.2 Taurine in human milk : growth modulator or conditionally essential amino acid? Gaull,G.E.
  44. J. Nutr. v.110 Growth depression in taurine-depleted infant monkeys Hayes,K.C.;Stephan,Z.F.;Sturman,J.A.
  45. J. Pediatr. v.116 Taurine depletion in very low birth weight infants receiving prolonged total parenteral nutrition : role of renal imaturity Zelikovic,I.;Chesney,R.W.;Friedman,A.L.;Ahlfors,C.E.
  46. Ann. Rev. Biochem. v.55 Taurine biological update Wright,C.E.;Tallan,H.H.;Lin,Y.Y.;Gaull,G.E.
  47. Physiol. Rev. v.48 Biochemistry and physiology of taurine and taurine derivatives Jacobsen,J.G.;Smith,L.H.
  48. Clinical and biological research series v.91 membranes in growth and development, progress Gaull,G.E.;Sturman,J.A.;Wen,G.Y.;Winiewski,H.M.;Hoffman,J.F.(ed.);Giebisch,G.H.(ed.)
  49. Unpublished data Kim,J.S.;Kim,E.S.