초록
버들치 Rhynchocypris oxycephalus의 등지느러미와 가슴지느러미를 연결하는 중간 부위 체측상처를 수술하여, 과립형성 조직 수축 특성과 치유율 및 2차 치유에 관하여 조사하였다. 수술 푸 생존율은 수술 직후 및 수술 후 7일에 대조군의 100%에 비해 각각 95%와 99% 이었다. 수술 후 14일과 42일 사이에 사망은 없었다. 수술후 7~21에 과립형성 조직은 상피화되었으며 수술 후 29일에 과립형성 조직은 상처 주변부로 정상 위치수축을 하였다. 수술 후 35일~42일에 과립형성 조직에는 collagen 섬유가 존재하였고 표피는 잘 분화된 , alarm 물질세포를 내포하고 있었으며 상처 부위의 표피는 모든 어류에서 조직학적으로 정사이어서, 상처 치유는 수술 35일 이내에 완전히 이루어졌다.
Rhynchocypris oxycephalus was incised through the midlateral line between the dorsal and pectoral fins and the wounds were closed with absorbable synthetic suture, and here we describe histological details on the nature of second-intention wound healing, rate of healing, and the nature of granulation tissue contraction. Postoperative survivals were 95% and 99%, compared to 100% for counterpart control fish, among fish at just and 7 days after surgery, respectively. By 14~42 days after surgery, fish had no mortality. The granulation tissue was epithelialized from day 7 through day 22 postsurgery. By 28 days postsurgery, the granulation tissue had contracted the wound margins into apposition. By 35~42 days postsurgery, the granulatin tissue contained collagen fiber and the epidermis contained well-differentiated alarm substance cells ; thus, the epidermis over the wound site was histologically normal in most fish, showed that wound healing was essentially complete within 35 days of surgery.