Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Inhibition Effects of Auricularia auricula-judae Methanol Extract on Lipid Peroxidation and Liver Damage in Benzo(a)pyrene-Treated Mice

목이버섯 메탄올 추출물이 벤조피렌(B(a)P) 투여한 마우스의 지질과산화 및 간 손상 억제에 미치는 영향

  • 이갑랑 (영남대학교 식품영양학과) ;
  • 장종선 (영남대학교 식품영양학과) ;
  • 김현정 (영남대학교 식품영양학과) ;
  • 배준태 (영남대학교 식품영양학과) ;
  • 박선희 (영남대학교 식품영양학과) ;
  • 이승언 (영남대학교 식품영양학과) ;
  • 김옥미 (영남대학교 식품영양학과)
  • Published : 1998.08.01
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Abstract

This study was undertaken to investigate the inhibition effects of Auricularia auricula-judae methanol extract in edible mushroom on lipid peroxidation and liver damage in benzo(a)pyrene(B(a)P)-treated mice. The activities of serum aminotransferase, cytochrome P-450, superoxide dismutase, catalase, glutathione peroxidase and the hepatic content of lipid peroxide after B(a)P-treatment was markedly increased than control but those levels were significantly decreased by the treatment of Auricularia auricula-judae methanol extract. Glutathione S-transferase activity and the hepatic glutathione content were decreased by B(a)P-treatment than control, but those were also inhibited by the treament of Auricularia auricula-judae methanol extract. These results suggest that Auricularia auricula-judae methanol extract have a protective effect on liver damage by B(a)P.

Keywords

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