KSBB Journal

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
권호 표지

Production of Xylitol by Catabolite Derepressed Mutant of Candida sp.

Candida sp.의 Catabolite Derepressed Mutant에 의한 Xylitol 생산

  • Published : 1998.02.01
Download PDF
⟨ Previous Next ⟩

Abstract

In order to produce xylitol from hemicellulose hydrolysate which is widely used as a substrate, the development of strain such as catabolite derepressed mutant is required. After treatment of Candida sp. with EMS, GM-17 and PM-34 as catabolite derepressed mutant were isolated from Candida guilliermondii and Candida parapsilosis, respectively. Mutant GM-17 and PM-34 simultaneously assimilated xylose and glucose during the fermentation. The specific xylose reductase and xylitol dehydrogenase activities of mutant strains were also higher than those of wild strains in glucose medium and mixed medium of glucose and xylose. The xylitol productivity and yield of mutant GM-17 and PM-34 were improved as compared to the wild types in the mixed medium. The xylitol productivity and yield of mutant GM-17 were 0.09 g/L·hr and 0.56 g-xylitol/g-xylose, and those of mutant PM-34 were 0.21 g/L·hr and 0.52 g-xylitol/g-xylose in the mixed medium, respectively.

Keywords

References

  1. J. Food Sci. v.45 A Quantitative Study of Mannitol, Sorbitol, Xylitol, and Xylose in Wild Berries and Commercial Fruits Makinen,K.K.;E.Soderling
  2. J. Biol. Chem. v.225 The L-xyulose-xylitol Enzyme and Other Polyol Dehydrogenase of Guinea Pig Liver Mitochondria Hollmann,S.;O.Touster
  3. 생물산업 v.8 no.2 발효감미료의 연구현황 및 전망 이우종;서진호
  4. Food Technol. v.10 Xylitol in Sugar free Confection Pepper,T.;P,M.Olinger
  5. Food Technol v.32 Xylitol : Its Properties and Food Applications Emodi,A.
  6. Process Biochem. v.30 no.2 Process for Fermentative Production fo Xylitol-a Sugar Substitute Nigam,P.;D.Singh
  7. Adv. Food. Res. v.25 Xylitol and Oral Health Makinen,K.K.
  8. U.S. Patent 4,008,285 Process for Making Xylitol Melaji,A.;L.hamalainen
  9. Agic. Biol. Chem. v.30 The Production of Xylitol, L-arabitol and Ribitol by Yeats Onishi,H.;T.Suzuki
  10. J. Ferment. Bioeng. v.67 Conversion of D-Xylose into Xylitol by Immobilized Cells of Candida pelliculosa and methanobacterium sp. HU Nishio,N.;K.Sugawa;N.Hayase;N.Nagai
  11. J. Ferment. Bioeng. v.67 Xylitol Production by a Methanol Yeast, Candida boidinii(Kloeckera sp.)No.2201 Vongsuvanlert,V.;Y.Tani
  12. Biotechnol. Lett. v.13 Xylitol Production from D-xylose by Candida guiliermondi: Fermentation Behaviour Meyrial,V.;J.P.Delgenes;R.Moletta;J.M.Navano
  13. Biotechnol. Lett. v.3 Quantitative Production of Xylitol from D-xylose by a High-xylitol Producing Yeast Mutant Candida tropicalis HXP2 Gong,C.H.;L.F.Chen;G.T.Tsao
  14. 한국농화학회지 v.39 no.3 Candida parapsilosis 돌연변이주에 의한 xylitol 생산조건의 최적화 오석근;김상용;김정회
  15. Process Biochem. v.29 Influence fo Oxygen on Ethnol and Xylitol Production by Xylose Fermenting Yeasts Furlan,S.A.;P.Bouilloud;H.F.de Castro
  16. Can. J. Microbiol. v.28 Fermentation of D-xylose, Xylitol and D-xyulose by Yeasts Maleszka,R.;H.Schneider
  17. Appl. Environ Microbiol. v.54 no.1 Induction of Xylose Reductase and Xylitol Dehydrogenase Activities in Pachysolen Tannophilus and Pichia stiptis in Mixted Sugars Bicho,P.A.;P.L.Runnals;J.D.Cunnigham;H.Lee
  18. Appl. Envrion. Microbiol. v.43 Sequential Utilization of Mixed Monosaccardes by Yeasts Hsiano,H.Y.;L.C.Chiang;P.P.Ueng;G.T.Tdao
  19. Appl. Microbiol. Biotechnol. v.23 The Fermentation of Hexose and Pentose Sugars by Candida shehatae and Pichia stipitis du Preez,J.C.;M.Bosch;B.A.Prior
  20. Biotechnol. Bioeng. Symp. v.12 Fermentation of Wheat Straw Hemicellulose to Ethanol by Pachsolen tannophilus Detroy,R.W.;R.I.Cunningham;A.I.Herman
  21. FEMS Microbiol. Rev. v.32 Catabolic Repression Mutants of Yeasts Gancedo,J.;C.Gancedo
  22. J. Microbiol. Biotechnol. v.3 no.2 Selective Isolation and Characterization of Schwanniomyces castellii Mutants with Increased Production of α-Amylase and Glucoamylase Ryu,Y.W.;S.H.Ko
  23. J. Biol. Chem. v.196 Protein Measurement with the Folin Phenol Reasent Lowry,O.H.;N.J.Rosebrough
  24. J.Ferment. Bioeng. v.79 no.3 Purification, Characterization and Structure Analysis of NADPH-Dependent D-xylose Reductase from Candida tropicalis Yokoyama,S.;T.Suzuki;K.Kawai;H.Horitsu;K.Takamizawa
  25. Biotechnol. Lett. v.17 no.11 Influence of Media Composition on Xylitol Fermentation by Candida guilliermondii Using Response Surface Methodology Roberto,I.C.;S.Sato;I.M. de Mancilfia;M.E.S.Taqueda
  26. Biotechnol. Lett. v.17 no.4 The Reduction of Xylose to Xylitol by Candida guilliermondii and Candida parapsilosis : Incidence of Oxygen and pH Nolleau,V.;L.Preziosi-Belloy;J.M.Navarro
  27. J. Ferment. Bioeng. v.81 no.2 Production of Xylitol from D-xylose by Candida tropicalis: the Effect of D-glucose Feedion Yahashi,Y.;H.Horitsu;K.Kawai;T.Suzuki;K.Takamizawa