Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
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Structural Analogues of Cumambrin B from the Flower of Chrysanthemum boreale

  • Jang, Dae-Sik (Department of Agricultural Chemistry, Gyeongsang National University) ;
  • Yang, Min-Suk (Department of agricultural chemistry, Gyeongsang National University) ;
  • Ha, Tae-Jung (Department of Agricultural Chemistry, Gyeongsang National University) ;
  • Park, Ki-Hun (Department of Agricultural Chemistry, Gyeongsang National University)
  • Published : 1998.10.01
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Abstract

The structural analogues of cumambrin B(1, 2, 3, 4) were isolated from the flower of Chrysnathemum boreale Makino. The structures of compounds were determined by two-dimensional $^{1}H-^{1}H$ COSY and $^{13}C-^{1}H$ COSY spectra with the aid of homonuclear and heteronuclear double resonance experiment. The stereochemistry of compounds has been verified from single crystal X-ray diffraction of cumambrin A(2). the antimicrobial activities of these guaianolides have been studied.

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References

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