Korean Journal of Clinical Pharmacy (한국임상약학회지)
- Volume 8 Issue 1
- /
- Pages.54-58
- /
- 1998
- /
- 1226-6051(pISSN)
- /
- 2508-786X(eISSN)
The Stability of Ceftriaxone Sodium Injection with the Various Storage Methods after Reconstitution
Ceftriaxone Sodium 주사제 조제후 보관방법에 따른 안정성
- Oh, Eun Joo (Graduate School of Clinical Pharmacy, Sookmyung Women's University) ;
- Park, Kwang Joon (Pharmacy of Children's Hospotal, Seoul Nationa University Hospital) ;
- Shin, Hyun Taek (Graduate School of Clinical Pharmacy, Sookmyung Women's University) ;
- Lee, Sukhyang (Graduate School of Clinical Pharmacy, Sookmyung Women's University)
- Published : 1998.05.01
Abstract
The stability of ceftriaxone sodium 100 mg/ml in the water for injection was tested at two temperature conditions (refrigerator and room temperature) and two storage containers (vitro and syringe). The stability of each sample was determined by high-performance liquid chromatography while storing for 5 days at room temperature and 27 days at refrigerator. The concentration of ceftriaxone sodium was 100 mg/ml which the hospital usually use as a filling preparation for I.V. push or Y-site injection. There was no significant difference between the storage in vials and syringes. There was no significant difference in the change of concentration until storing the reconstituted ceftriaxone sodium injection for 2 days at room temperature and 14 days at refrigerator. In conclusion, the ceftriaxone sodium 100 mg/ml in the water for injection can be stored in vial or syringe for 2 days at room temperature and 14 days at refrigerator after preparation.