Korean Journal of Clinical Pharmacy (한국임상약학회지)
- Volume 8 Issue 1
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- Pages.13-18
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- 1998
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- 1226-6051(pISSN)
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- 2508-786X(eISSN)
Clinical Pharmacokinetics of Vancomycin in Ovarian Cancer Patients
난소암 환자에서 반코마이신의 임상약물동태
- Kim, Yang Woo (College of Pharmacy, Chosun University) ;
- Choi, Jun Shik (College of Pharmacy, Chosun University) ;
- Lee, Jin Hwan (College of Pharmacy, Chosun University) ;
- Park, Jae Young (College of Pharmacy, Chosun University) ;
- Choi, Byong Chul (College of Pharmacy, Chosun University) ;
- Burm, Jin Pil (College of Nursing, Chosun University)
- 김양우 (조선대학교 약학대학) ;
- 최준식 (조선대학교 약학대학) ;
- 이진환 (조선대학교 약학대학) ;
- 박재영 (조선대학교 약학대학) ;
- 최병철 (조선대학교 약학대학) ;
- 범진필 (조선대학교 간호전문대학)
- Published : 1998.05.01
Abstract
The purpose of this study was to determine pharmacokinetic parameters of vancomycin using the compartment model dependent and compartment model independent analysis in 6 Korean normal volunteers and 8 ovarian cancer patients. Vancomycin was administered 1.0 g bolus by IV infusion over 60 minutes. The elimination rate constant (
Keywords
- Clinical pharmacokinetics;
- Vancomycin;
- Ovarian cancer;
- Compartment model de-pendent analysis;
- Compartment model independent analysis