Radiation Oncology Journal
- Volume 16 Issue 4
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- Pages.447-454
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- 1998
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- 2234-1900(pISSN)
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- 2234-3156(eISSN)
Post-operative Radiation Therapy for Esophageal Cancer; Analysis of Failure Pattern
식도암의 수술 후 방사선 치료: 실패 양상 분석
- Kim Mi Sook (Department of Radiation Oncology, Korea Cancer Center Hospital) ;
- Kim Jae Young (Department of Radiation Oncology, Korea Cancer Center Hospital) ;
- Yoo Seoung Yul (Department of Radiation Oncology, Korea Cancer Center Hospital) ;
- Zo Chul Goo (Department of Radiation Oncology, Korea Cancer Center Hospital) ;
- Yoo Hyung Jun (Department of Radiation Oncology, Korea Cancer Center Hospital) ;
- Zo Jae Ill (Department of Thoracic Surgery, Korea Cancer Center Hospital) ;
- Baek Hee Jong (Department of Thoracic Surgery, Korea Cancer Center Hospital) ;
- Park Jong Ho (Department of Thoracic Surgery, Korea Cancer Center Hospital) ;
- Choi Soo Yong (Department of Laboratory of Clinical Research, Korea Cancer Center Hospital)
- 김미숙 (원자력병원 방사선종양학과) ;
- 김재영 (원자력병원 방사선종양학과) ;
- 류성렬 (원자력병원 방사선종양학과) ;
- 조철구 (원자력병원 방사선종양학과) ;
- 유형준 (원자력병원 방사선종양학과) ;
- 조재일 (원자력병원 흉부외과) ;
- 백희종 (원자력병원 흉부외과) ;
- 박종호 (원자력병원 흉부외과) ;
- 최수용 (원자력병원 임상의학연구실)
- Published : 1998.12.01
Abstract
Purpose : This study evaluated the survival, local control, prognostic factor, and failure pattern of patients with esophageal cancer treated with operation and adjuvant radiation therapy to use as fundermental data of postoperative radiation therapy. Materials and Methods : A retrospective analysis was undertaken of 82 patients who had locally advanced esophageal cancer treated with operation and adjuvant radiation therapy from January 1988 to December 1995. According to AJCC staging, stage IIA were in 26 patients, stage IIB in 4 patients, and stage III in 52 patients. Squamous cell carcinoma were in 77 patients, adenosquamous carcinoma in 3 patients, and adenocarcinoma in 2 patients. The patients received radiation therapy ranging from 41.0 Gy to 64.8 Gy. Five patients received neoadjuvant chemotherapy. Results : Two-year survival and local control rates for all patients were 36.8
목적 : 국소 제어율과 생존율, 여러 예후인자 및 국소실패의 원인을 분석하므로 식도암의 수술 후 방사선 치료에 기본 자료로 활용하고자 한다. 대상 및 방법 : 1988년 1월부터 1995년 12월까지 본원에서 수술을 시행 후 40Gy 이상의 방사선 치료를 받은 국소적으로 진행된 식도암 환자 82명을 대상으로 후향적 분석을 하였다. 수술 후 병기는 II가 26례, IIB가 4례, III가 52례 였으며 수술후 병리학 소견으로 편평상피암 77례, Adenosquamous 3례, 선암 2례였다. 수술 후 외부 방사선 치료로 41Gy에서 64.8Gy(중간값 50.4Gy)를 조사하였다. 5례에서 PFC 항암화학요법을 시행하였다. 결과 : 총 환자의 2년 생존율 및 2년 국소제어율은 각각 36.8