Journal of Oriental Neuropsychiatry (동의신경정신과학회지)

The Korean Society of Oriental Neuropsychiatry (대한한방신경정신과학회)
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A Study on Effect of Soeuminsohabhyangwon on the Brain Serotonin contents of Stressed Mice

소음인(少陰人) 소합향원(蘇合香元)이 Stress 생쥐의 뇌(腦) Serotonin 함량(含量)에 미치는 영향(影響)

  • Kwen Soon-Ju (Dept. of Oriental Neuropsychiatry, College of Oriental Medicine, Kyung San University) ;
  • Chung Dae-Kyoo (Dept. of Oriental Neuropsychiatry, College of Oriental Medicine, Kyung San University) ;
  • Kim Yun-Sub (College of Oriental Medicine, Kyungwon University)
  • 권순주 (경산대학교 한의과대학 신경정신과학교실) ;
  • 정대규 (경산대학교 한의과대학 신경정신과학교실) ;
  • 김연섭 (경원대학교 한의과대학)
  • Published : 1998.12.30
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Abstract

This study was aimed to evaluate the anti-stress effect of Soeuminsohabhyangwon on the mice in Cold and Swimming stress.In order to investigate the anti-stress effect of Soeuminsohabhyangwon in Cold and Swimming stressed mice, the serotonin contents were measured by HPLC method in various part of mouse brain The following results were observed. 1. In Cerebral Cortex of Frontal Lobe, the serotonin content was decreased in the Control group as compared with Normal group and the serotonin content was increased in the SHW group as compared with Control group. 2. In hypothalamus, the serotonin content was decreased in the Control group as compared with Normal group and the serotonin content was increased with statistical significance in the SHW group as compared with Control group. 3. In corpus striatum, the serotonin content was decreased in the Control group as compared with Normal group and the serotonin content was increased with statistical significance in the SHW group as compared with Control group. 4. In hippocampus, the serotonin content was decreased in the Control group as compared with Normal group and the serotonin content was increased with statistical significance in the SHW group as compared with control group.Base on the above results, it may be concluded that Soeuminsohabhyangwon are effective to reduce stress.

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References

  1. 萬病回春 v.3 공廷賢
  2. 한의학의 형성과 체계 金完熙;金廣中
  3. 東醫神經精神枓學會誌 v.4 no.1 스트레스의 한의학적 이해 金鐘佑;金知赫;黃義完
  4. 東醫神經精神科學會誌 v.8 no.1 養心湯 및 養心湯加체葉이 구속스트레스 흰쥐의 뇌부위별 Catecholamine함량에 미치는 영향 宋必正;鄭大奎
  5. 三和散의 항Stress 및 鎭痛에 對한 實驗的 硏究 李和信
  6. 臟腑辨證論治 v.3 金完熙;崔達永(共編)
  7. 역동정신의학 金鐘柱
  8. 慶熙醫學 v.6 no.4 蘇合香元의 항심리적스트레스효과에 관한 실험적 연구 金知赫;黃義完
  9. 牛黃淸心元과 蘇合香元의 효능에 관한 연구 南相璟;李京燮
  10. 東醫病理學 文濬典;安圭錫;崔昇勤(共編)
  11. 東醫神經精神科學會誌 v.2 no.1 스트레스에 관한 문헌적 고찰 문충모;김지혁;황의환
  12. 최신정신의학 v.3 민성길
  13. 中草藥學 v.2 上海中醫學院(編)
  14. 方證新編 宋炳基
  15. 四關穴針刺와 麝香蘇合元이 鎭痛 抗痙攣 抗瀉下 血淸性分變化 및 위기능에 미치는 영향 安榮基
  16. 東醫處方大全 廉泰煥
  17. 최신임상정신의학 이근후(외)
  18. 精神醫學辭典 李丙允
  19. 本草學 李尙仁
  20. 심리학 이수원(외)
  21. 安定湯이 拘束Stress 흰쥐의 血液 및 尿 Catecholamine 含量 에 미치는 影響 李政祜
  22. 東醫壽世保元 李濟馬
  23. 四象醫學 全國韓醫科大學 四象醫學敎室(編)
  24. 少陰人 蘇合香元의 효능에 관한 실험적 연구 全震相;宋－炳
  25. 醫門寶鑑 周命新
  26. 太平惠民和劑局方 陳師文
  27. 山東中醫學院 校釋，黃帝內經素問校釋 上冊 v.2 河北醫學院
  28. 東醫寶鑑 許俊
  29. 심리학개론 v.2 홍대식(譯)
  30. 方藥合編 v.3 黃度淵
  31. 心身症 黃義完
  32. 東醫精神醫學 v.3 黃義完;金知赫
  33. J. Chromatography v.360 Simple method for the stimutaneous determination of acetycholine, choline, noradrenaline, dopamine and serotonin in brain tissue by high performance liquid chromatography with electrochemical detetion Jeneda, N.;Asano. M.;Nagatsu. T.
  34. Modern Clinical Psychisty Kolb. L.C.
  35. Introduction to psychology(2nd ed) Levinthal. C.F.
  36. Canada, Med.Ass.J v.34 The alarm reaction. Selye. H.
  37. The stress of life Selye. H.
  38. Analytic Chemistry v.49 Determination of serotonin and dopamine in mouse brain tissue by high performance liquid chromatography with electrochemical detection Suleiman. S.;Leroy. B.C.
  39. Brain Maps(Structure of the Rat Brain) Swanson. L.W.