생약학회지 (Korean Journal of Pharmacognosy)
- 제29권4호
- /
- Pages.323-330
- /
- 1998
- /
- 0253-3073(pISSN)
- /
- 2288-9299(eISSN)
인체암세포주에 대한 천연자원의 세포독성 검색 (I)
Cytotoxic Activities of Herbal Drugs against Human Cancer Cell Lines (I)
-
Park, Jong-Dae
(Korea Ginseng & Tobaco Research Institute) ;
- Kim, Shin-Il (Korea Ginseng & Tobaco Research Institute) ;
- Lee, You-Hui (Korea Ginseng & Tobaco Research Institute)
- 발행 : 1998.12.30
초록
For the search of new antineoplastic agents from natural resources, two hudred and one kinds of oriental medicinal drugs were extracted with petroleum ether/ether(1:1), ethyl acetate and methyl alcohol, successively and their cytotoxicities were evaluated against A549 (human lung carcinoma) and SK-OV-3 (human ovary adenocarcinoma) cell lines. Among them, thirty kinds of ether extracts, forty-one kinds of ethyl acetate extracts and nine kinds of methanol extracts showed significant cytotoxic activities (above 70% inhibition) against A549 cell lines at a concentration of