Korean Journal of Pharmacognosy (생약학회지)
- Volume 29 Issue 4
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- Pages.323-330
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- 1998
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Cytotoxic Activities of Herbal Drugs against Human Cancer Cell Lines (I)
인체암세포주에 대한 천연자원의 세포독성 검색 (I)
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Park, Jong-Dae
(Korea Ginseng & Tobaco Research Institute) ;
- Kim, Shin-Il (Korea Ginseng & Tobaco Research Institute) ;
- Lee, You-Hui (Korea Ginseng & Tobaco Research Institute)
- Published : 1998.12.30
Abstract
For the search of new antineoplastic agents from natural resources, two hudred and one kinds of oriental medicinal drugs were extracted with petroleum ether/ether(1:1), ethyl acetate and methyl alcohol, successively and their cytotoxicities were evaluated against A549 (human lung carcinoma) and SK-OV-3 (human ovary adenocarcinoma) cell lines. Among them, thirty kinds of ether extracts, forty-one kinds of ethyl acetate extracts and nine kinds of methanol extracts showed significant cytotoxic activities (above 70% inhibition) against A549 cell lines at a concentration of