Korean Journal of Pharmacognosy (생약학회지)
- Volume 29 Issue 1
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- Pages.48-55
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- 1998
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Effects of the Administration of Bezoar Bovis on Immune Responses of Mice
우황이 생쥐의 면역반응에 미치는 영향
-
Son, Eun-Wha
(Sung Kyun Kwan University, College of Pharmacy) ;
- Park, Jae-Hyun (Sung Kyun Kwan University, College of Pharmacy) ;
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Kim, Kyung-Ran
(Sung Kyun Kwan University, College of Pharmacy) ;
- Kim, Byung-O (Sung Kyun Kwan University, College of Pharmacy) ;
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Rhee, Dong-Kwon
(Sung Kyun Kwan University, College of Pharmacy) ;
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Pyo, Suhk-Neung
(Sung Kyun Kwan University, College of Pharmacy)
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손은화
(성균관대학교 약학대학) ;
- 박재현 (성균관대학교 약학대학) ;
-
김경란
(성균관대학교 약학대학) ;
- 김병오 (성균관대학교 약학대학) ;
-
이동권
(성균관대학교 약학대학) ;
-
표석능
(성균관대학교 약학대학)
- Published : 1998.03.30
Abstract
The effects of Bezoar Bovis on immune responses of ICR Mice were studied. In the present study, the Jerne hemolytic plaque assay (PFC) was used to evaluate the humoral immune response to sheep red blood cells, and macrophage regulatory function was measured by quantitating the production of molecules secreted by macrophages. Bezoar Bovis was given in single daily p.o doses for short term (1, 2 days) or long term (7, 14 days). PFC response for taken 3 days after short term exposure to Bezoar Bovis was increased. The production of nitirc oxide in macrophages was also stimulated. In contrast, long term exposure to Bezoar Bovis resulted in inhibitory effect of Bezoar Bovis on nitirc oxide,