Antihepatotoxic Activity of Cassia tora Leaf Extract

  • Maity, Tapan K. (College of Pharmaceutical Sciences) ;
  • Mandal, Subhash C. (Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University) ;
  • Pal, M. (Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University) ;
  • Saha, B.P. (Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University)
  • Published : 1998.12.01

Abstract

Methanolic extract of Cassia tora leaves was evaluated for its hepatoprotective activity in rats by inducing hepatotoxicity with paracetamol (acute model). The extract at a dose of 400 mg/kg orally exhibited significant protective effect by lowering the serum levels of transaminase (SGOT and SGPT), bilirubin, and alkaline phosphatase (ALP). The effects produced were comparable to that of a standard hepatoprotective agent.

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