Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Ficus racemosa Affords Antihepatotoxic Activity Against Paracetamol-Induced Acute Liver Damage in Rats

  • Mandal, Subhash C. (Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University) ;
  • Maity, Tapan K. (Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University) ;
  • Das, J. (Department of Pharmacology Dr. B.C. Roy P.G. Institute of Basic Medical Sciences, University College of Medicine, University of Calcutta) ;
  • Saha, B.P. (Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University) ;
  • Pal, M. (Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University)
  • Published : 1998.09.01
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Abstract

The effect of oral treatment with Ficus racemosa leaf extract (400 mg/kg for seven days) were studied on hepatic damage induced by paracetamol (750 mg/kg, i.p.) in rats. Biochemical parameter like SGOT, SGPT, serum bilirubin and alkaline phosphatase were estimated to assess liver function. These biochemical observations were supplemented by histopathological examination of liver sections. The activity of extract was also comparable to Neutrosec a known hepatoprotective formulation.

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