Alkaloids from Amaryllidaceae III -Alkaloids from the Bulbs of Pancratium maritimum-

The extract from the bulbs of Pancratium maritimum L. afforded 12 alkaloids belonging to the skeletally six different groups of the Amaryllidaceae alkaloids. In this paper, the isolation and identification of (-)-N-demethyl-galanthamine (1), (+)-tazettine (2) and (-)-2-O-demethylmontanine (3) are described. Their structures have been determined by using extensive spectroscopic techniques. This is the first report describing the occurrence of 1 and 3 in this plant.