한국균학회지 (The Korean Journal of Mycology)

한국균학회 (The Korean Society of Mycology)
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까치버섯 (Polyozellus multiflex)이 생산하는 미량 유기화합물의 화학구조

Structure Elucidation of Minor Organic Constituents from Polyozellus multiflex

  • 황지숙 (한국과학기술연구원 생명공학연구소) ;
  • 류종하 (경북대학교 농과대학 농화학과) ;
  • 구교철 (경북대학교 농과대학 농화학과) ;
  • 곽주연 (경북대학교 농과대학 농화학과) ;
  • 김상인 (경북대학교 농과대학 농화학과) ;
  • 유익동 (한국과학기술연구원 생명공학연구소) ;
  • 송경식 (경북대학교 농과대학 농화학과)
  • Hwang, Ji-Sook (Korea Research Institute of Bioscience and Biotechnology, KIST) ;
  • Ryu, Jong-Ha (Department of Agricultural Chemistry, Kyungpook National University) ;
  • Gu, Gyo-Cheol (Department of Agricultural Chemistry, Kyungpook National University) ;
  • Kwak, Ju-Yeon (Department of Agricultural Chemistry, Kyungpook National University) ;
  • Kim, Sang-In (Department of Agricultural Chemistry, Kyungpook National University) ;
  • Yoo, Ick-Dong (Korea Research Institute of Bioscience and Biotechnology, KIST) ;
  • Song, Kyung-Sik (Department of Agricultural Chemistry, Kyungpook National University)
  • 발행 : 1998.12.30
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초록

국내 자생버섯인 까치버섯(Polyozellus multiflex의 메탄을 추출물로부터 이 버섯이 생산하는 2차 대사산물을 조사한 결과 기 보고된 주 2차 대사산물인 polyozellin 이외에 미량 2차 대사산물로서 4가지 화합물이 단리되었으며 이들은 각종 spectral analysis에 의하여 각각 ergost-4,6,8,22-tetraen-3-one, 4-methoxy-6-methyl-2H-pyran-2-one, p-anisic acid, 및 p-hydroxybenzoic acid로 동정되었다. 이들에 대하여 prolyl endopeptidase 및 acetylcholine esterase에 대한 저해 활성을 측정하였으나 최고 100 ppm의 농도에서도 저해활성을 나타내지 못하였다.

Four minor compounds were isolated from fruiting bodies of Polyozellus multiflex by consecutive chromatographic separation. Their structures were identified as ergost-4,6,8,22-tetraen-3-one, 4-methoxy-6-methyl-2H-pyran-2-one, p-anisic acid, and p-hydroxybenzoic acid by spectral analysis. They could not inhibit prolyl endopeptidase nor acetylcholine esterase at the concentration up to 100 ppm.

키워드

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