The Journal of Internal Korean Medicine (대한한방내과학회지)
- Volume 19 Issue 2
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- Pages.208-218
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- 1998
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- 1226-9174(pISSN)
Effects of Buthus martensi Karsch on immune response in mice of different ages
전갈(全蝎)이 노령(老齡)에 따른 mouse의 면역(免疫) 기능(機能)에 미치는 영향(影響)
- Jeong In-Chae (Dept. of Internal Medicine, College of Oriental Medicine Dongguk University) ;
- Jeong Ji-Cheon (Dept. of Internal Medicine, College of Oriental Medicine Dongguk University)
- Published : 1998.12.01
Abstract
To clarify the activating effects of Buthus martensi Karsch on immunological function, its effect on primary and secondary antibodies production in mice of various ages was investigated. Buthus martensi Karsch increased the number of both antibody producing cells(anti-IgM and anti-IgG producing plaque forming cells, PFC) and phagocytic activity of peritoneal macrophage. Futhermore, these phenomena were significantly increased with aging in mice. Buthus martensi Karsch also increased natural killer cell activity concerning to cancer immunology. These results suggest that Buthus martensi Karsch markedly increases the reduced activity in the elderly and activates the immune response in senescence mice.