대한한방내과학회지 (The Journal of Internal Korean Medicine)
- 제19권2호
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- Pages.208-218
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- 1998
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- 1226-9174(pISSN)
전갈(全蝎)이 노령(老齡)에 따른 mouse의 면역(免疫) 기능(機能)에 미치는 영향(影響)
Effects of Buthus martensi Karsch on immune response in mice of different ages
- Jeong In-Chae (Dept. of Internal Medicine, College of Oriental Medicine Dongguk University) ;
- Jeong Ji-Cheon (Dept. of Internal Medicine, College of Oriental Medicine Dongguk University)
- 발행 : 1998.12.01
초록
To clarify the activating effects of Buthus martensi Karsch on immunological function, its effect on primary and secondary antibodies production in mice of various ages was investigated. Buthus martensi Karsch increased the number of both antibody producing cells(anti-IgM and anti-IgG producing plaque forming cells, PFC) and phagocytic activity of peritoneal macrophage. Futhermore, these phenomena were significantly increased with aging in mice. Buthus martensi Karsch also increased natural killer cell activity concerning to cancer immunology. These results suggest that Buthus martensi Karsch markedly increases the reduced activity in the elderly and activates the immune response in senescence mice.