Journal of the Korean Academy of Child and Adolescent Psychiatry
- Volume 8 Issue 2
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- Pages.266-272
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- 1997
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- 2233-9183(eISSN)
A CLINICAL TRIAL OF FLUOXETINE IN THE TREATMENT OF SELECTIVE MUTISM
선택적 함구증 환자에서의 Fluoxetine 치험
- Park, Min-Sook (Dr. Park's Neuropsychiatric Clinic) ;
- Nam, Soo-Yong (Department of Psychiatry, College of Medicine, Yonsei University) ;
- Yook, Ki-Hwan (Department of Psychiatry, College of Medicine, Yonsei University) ;
- Noh, Kyung S (Department of Psychiatry, Kangbuk Samsung Hospital College of Medicine, Seongkyunkwan University) ;
- Lee, Hong-Shick (Department of Psychiatry, College of Medicine, Yonsei University) ;
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Song, Dong-Ho
(Department of Psychiatry, College of Medicine, Yonsei University)
- 박민숙 (박민숙 신경정신과의원) ;
- 남수용 (연세대학교 의과대학 정신과학교실) ;
- 육기환 (연세대학교 의과대학 정신과학교실) ;
- 노경선 (성균관대학교 의과대학 강북삼성병원 정신과) ;
- 이홍식 (연세대학교 의과대학 정신과학교실) ;
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송동호
(연세대학교 의과대학 정신과학교실)
- Published : 1997.12.31
Abstract
We examine the clinical efficacies of fluoxetine in treating the children with selective mutism. In an 8-week open-label clinical study, 17 children with selective mutism are received 20-60mg/day of fluoxetine. Our results reveal that 13 subjects(76%) of 17 subjects improve statistically in within subjects comparison of pre- and post-treatment changes in the scores of Clinical Global Impression scale for mutism, Children’s Depression Inventory scale, and Revised Children’s Manifest Anxiety Scale. These data suggest that selective serotonergic antidepressants may be effective in treating selective mutism in children and adolescents.
본 연구의 목적은 선택적 함구증 환자에게 강력한 세로토닌 재흡수 억제제인 fluoxetine을 투여한 후에 임상효과를 검증하고자 하였다. 대상은 선택적 함구증 환아 17명으로 8주간 fluoxetine