Journal of the Korean Academy of Child and Adolescent Psychiatry
- 제8권1호
- /
- Pages.133-138
- /
- 1997
- /
- 2233-9183(eISSN)
Prader-Willi 증후군의 Fluoxetine 치험 1례
A CASE OF PRADER-WILLI SYNDROME TREATED WITH FLUOXETINE
- Shin, Dong-Won (Department of Psychiatry, College of Medicine, Yonsei University) ;
- Song, Dong-Ho (Department of Psychiatry, College of Medicine, Yonsei University)
- 발행 : 1997.06.30
초록
Prader-Willi 증후군(Prader-Willi Syndrome, PWS)은
Prader Willi Syndrome(PWS) was first recognized and reported by Prader-Willi. The etiology of the syndrome is not fully understood, but 50-70% of the patients show small deletion in chromosome 15. Manifested symtoms vary according to developmental age. In early life, hypotonia, areflexia, feeding difficulties, hypothermia, microgenitalia, hypoplastic scrotum, cryptochordism were observed. But in several years, hypotonia disappears, and polyphagia, decreased satiety, psychomotor retardation, obesity, hypogonadism and short stature become main problems. Behavioural problems including temper and aggressive outbursts, stealing food, hoarding food, and self excoriating skin picking, trichotillomania are more prominent during adolescence and young adulthood. Also, irritable, depressed mood are described. Lots of psychological and behavioural problems explain the reason why psychiatrists have managed and reported this syndrome. However, there has been no official report of PWS in our country. So authors report the clinical characteristics and issues in management of a patient with PWS.