Journal of Technologic Dentistry (대한치과기공학회지)
- Volume 19 Issue 1
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- Pages.113-120
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- 1997
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- 1229-3954(pISSN)
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- 2288-5218(eISSN)
Isolation of Candida albicans from Denture Patients and in Vitro Activities of Amphotericin B and Miconzole
의치환자에서 Candida albicans분리와 amphotericin B 및 miconazole에 시험관내 감수성
- Shin, Moo-Hak (Dept. of Dental Laboratory Technology, Wonkwang Health College) ;
- Kim, Shin-Moo (Dept. of Medical Technology, Wonkwang Health College)
- Published : 1997.11.15
Abstract
Candida albicans is now well recognized among the denture stomatitis patients. The broth macrodilution test is the most widely used technique for antifungal susceptibility testing. The purpose of this study was to determine the C. albicans carrier rate of the denture patients in Iksan, chonbuk. To determine the C. albicans carrier rate of denture patients, culture were made from 227 sample taken in Iksan, Chonbuk during July 1997 to August 1997. Also activities of amphotericin B and miconzole against isolates of denture patients of C. albicans were tested by broth macrodilution test using RPMI medium 1640. The results were as follows : First C. ablicans was isolated from 6.6% of denture patients samples and the frequency of isolation fo C. albicans was highest(50%) in the age group of 71-year-old to 80-year-old denture patients. Second, against C. albicans, the MIC range of amphotericn B was