Tuberculosis and Respiratory Diseases
- 제44권6호
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- Pages.1419-1425
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- 1997
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- 1738-3536(pISSN)
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- 2005-6184(eISSN)
Klinefelter 증후군에 병발된 재발한 원발성 종격동 비정상피종 1예
A Case of Recurred Primary Mediastinal Nonseminomatous Germ Cell Tumor Associated with Klinefelter's Syndrome
- 진원종 (한국보훈병원 내과) ;
- 신규석 (한국보훈병원 내과) ;
- 박태현 (한국보훈병원 내과) ;
- 서정환 (한국보훈병원 내과) ;
- 이귀래 (한국보훈병원 내과) ;
- 노용호 (한국보훈병원 내과) ;
- 김정례 (한국보훈병원 해부병리과) ;
-
이석형
(가톨릭대학교 의과대학 병리학교실)
- Jin, Won-Jong (Department of Internal Medicine, Korea Veterans Hospital) ;
- Shin, Kyu-Suck (Department of Internal Medicine, Korea Veterans Hospital) ;
- Park, Tae-Hyun (Department of Internal Medicine, Korea Veterans Hospital) ;
- Suh, Jung-Hwan (Department of Internal Medicine, Korea Veterans Hospital) ;
- Lee, Gwi-Lae (Department of Internal Medicine, Korea Veterans Hospital) ;
- Roh, Yong-Ho (Department of Internal Medicine, Korea Veterans Hospital) ;
- Kim, Jeong-Rye (Department of Pathology, Korea Veterans Hospital) ;
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Lee, Sug-Hyung
(Department of Pathology, Catholic University Medical College)
- 발행 : 1997.12.31
초록
저지들은 재발된 원발성 종격동 비정상피종과 동반된 Klinefelter 증후군 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.
Primary mediastinal nonseminomatous germ cell tumor associated with Klinefelter's syndrome is a rare disorder. We experienced a case of recurred primary mediastinal nonseminomatous germ cell tumor developed in a 24-year-old patient with Klinefelter's syndrome. The patient had been treated with surgery and combination chemotherapy under the diagnosis of primary mediastinal nonseminomatous germ cell tumor before. A round mass was found on the right lower lung field in the chest X-ray during follow up. The patient was diagnosed as recurred primary nonseminomatous genu cell tumor and Klinefelter's syndrome through tumor markers, peripheral blood karyotyping, and other tests including hormonal assay and was treated with combination chemotherapy and surgery again. When the patient is diagnosed as primary mediastinal nonseminomatous germ cell tumor, Klinefelter's syndrome and hematologic malignancies should be considered to be associated diseases and vice versa.