Tuberculosis and Respiratory Diseases
- Volume 44 Issue 4
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- Pages.930-934
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- 1997
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- 1738-3536(pISSN)
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- 2005-6184(eISSN)
A Case of Thrombocytopenia and Purpura Induced by Rifampin, Pyrazinamide, and Ciprofloxacin
Rifampin, Pyrazinamide and Ciprofloxacin에 의한 혈소판 감소증, 자반증 1예
- Son, Hyung-Dae (The Department of Chest Medicine, National Medical Center) ;
- Kim, Chang-Sun (The Department of Chest Medicine, National Medical Center) ;
- Park, Mi-Ran (The Department of Chest Medicine, National Medical Center) ;
- Seo, Ji-Yung (The Department of Chest Medicine, National Medical Center) ;
- Rheu, Nam-Soo (The Department of Chest Medicine, National Medical Center) ;
- Cho, Dong-Il (The Department of Chest Medicine, National Medical Center)
- 손형대 (국립의료원 흉부내과) ;
- 김창선 (국립의료원 흉부내과) ;
- 박미란 (국립의료원 흉부내과) ;
- 서지영 (국립의료원 흉부내과) ;
- 류남수 (국립의료원 흉부내과) ;
- 조동일 (국립의료원 흉부내과)
- Published : 1997.08.31
Abstract
Drug-induced thrombocytopenia and purpura have been developed by many various agents. Rifampin and Pyrazinamide have been known as bactericidal antituberculous drugs, but, the above side effects have been a problem. Especially, hematologic side effects are fatal to patients occasionally. Rifampin-induced thrombocytopenia and purpura have been well known, also, pyrazinamide-induced thrombocytopenia have been reported. A new quilonone agent, Ciprofloxacin, has been commonly used in clinics now, but it's side effects are not known well. So, we report a case of a 23-year-old female with thrombocytopenia and purpura after taking Rifampin, Pyrazinamide, and Ciprofloxacin as antituberculous agents.
저자들은 RF, PZA, Cipro. 에 의하여 발생한 것으로 추정되는 혈소판 감소증과 자반증이 나타난 환자 1예를 경험하였기에 문한 고찰과 함께 보고하는바이다.