A STUDY ON THE INHIBITORY EFFECT OF ARECA CATECHU L. ON THE ACID PRODUCTION OF STREPTOCOCCUS MUTANS JC-2 AND ITS CYTOTXICITY

빈랑의 Streptococcus mutans JC-2의 산생성 억제효과와 세포독성에 대한 연구

  • Lee, Gwang-Hee (Dept. of Dental Hygiene, Wonk wang Public Health College) ;
  • Nam, Yong-Ok (Dept. of Dental Hygiene, Wonk wang Public Health College)
  • 이광희 (원광보건전문대학 치위생과) ;
  • 남용옥 (원광보건전문대학 치위생과)
  • Published : 1997.09.30

Abstract

In order to develop natural anticariogenic agents, we investigated inhibitory effects of Areca catechu L. extracts on the acid production of Streptococcus mutans JC-2 and its cytotoxicity on NIH 3T3 fibroblasts were also examined. The results are as follows : 1. Major organic acid produced by Streptococcus mutans JC-2 were lactic acid and acetic acid, and their productions were decreased by additions of Areca catechu L. extracts. 2. Areca catechu L. extracts were showed noncytotoxicity on NIH 3T3 fibroblasts.

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Acknowledgement

Supported by : 원광보건전문대학