Korean Journal of Veterinary Research (대한수의학회지)
- Volume 37 Issue 2
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- Pages.281-289
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- 1997
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- 2466-1384(pISSN)
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- 2466-1392(eISSN)
Immunohistochemical application of anti-proliferating cell nuclear antigen antibody on the development of uterus following sex hormone administration in rats
성 hormone이 rat 자궁 발달에 미치는 영향에 대한 proliferating cell nuclear antigen 항체의 면역조직학적 응용
- Koh, Phil-ok (College of Veterinary Medicine Gyeongsang National University) ;
- Kwak, Soo-dong (College of Veterinary Medicine Gyeongsang National University)
- Received : 1997.03.20
- Published : 1997.06.25
Abstract
The study was designed to investigate the effects of progesterone and estrogen on the uterus of rats by immunohistochemical methods using Proliferating Cell Nuclear Antigen (PCNA) antibody. Eighteen female rats(Wistar), weighing initially about 300g, were ovariectomized. These rats were divided into four groups, progesterone-treated group, estrogen-treated group, estrogen+progesterone-treated group, and control group, progesterone-treated group was injected with 1mg of progesterone per rat per day for 2 days and estrogen-treated group with