Journal of Periodontal and Implant Science
- 제27권4호
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- Pages.685-700
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- 1997
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- 2093-2278(pISSN)
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- 2093-2286(eISSN)
MC3T3-E1 세포의 ALP activity에 대한 PDGF-BB의 영향
The Effects of PDGF-BB on the ALP Activity of MC3T3-E1 Cells
- 이경희 (경북대학교 치과대학 치주과학교실) ;
- 이재목 (경북대학교 치과대학 치주과학교실) ;
- 최병주 (경북대학교 치과대학 치과약리학교실) ;
- 유현모 (경북대학교 치과대학 구강생화학교실) ;
- 서조영 (경북대학교 치과대학 치주과학교실)
- Lee, Kyung-Hee (Department of Periodontology, School of Dentistry, Kyungpook National University) ;
- Lee, Jae-Mok (Department of Periodontology, School of Dentistry, Kyungpook National University) ;
- Choi, Byung-Ju (Department of Dental Pharmacology, School of Dentistry, Kyungpook National University) ;
- Yu, Hyun-Mo (Department of Oral Biochemistry, School of Dentistry, Kyungpook National University) ;
- Suh, Jo-Young (Department of Periodontology, School of Dentistry, Kyungpook National University)
- 발행 : 1997.12.31
초록
The ultimate aim of periodontal treatment is periodontal regeneration, which necessiates the regeneration of bone tissues. This paper investigated the effect of growth factor on bone cells. Platelet-derived growth factor(PDGF) is the one of the polypeptide growth factor that has been reported as a biological mediator which regulates activities of the cell proliferation, migration and metabolism of undifferentiated mesenchymal cells. The purpose of this study is to evaluate the effects of PDGF on bone nodule formation and ALP activity of MC3T3-El cells. Cells were seeded at
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