합성 ABA 유도체의 벼 유묘 생장저해 작용

Synthesis of Abscisic Acid Analogs and Their Biological Activity on Growth of Rice Seedling

천연의 (S)-(+)-ABA 보다 우수한 생육저해 활성을 갖는 ABA 유도체를 개발하기 위한 연구의 일환으로 p-hydroxy methyl cinnamate와 umbelliferone을 (S)-(+)-2-cis, 4-trans-ABA에 ester 결합시켜서 ABA-methyl cinnamate ester(AC)와 ABA-umbelliferone ester(AU) 화합물을 각각 83%와 78%의 높은 수율로 얻었다. 이들의 벼 유묘 생육저해 활성은 (+)-ABA에 비해서 AC가 $3{\sim}10$배, AU가 $10{\sim}30$배 정도로 훨씬 더 강한 활성을 보였다.

This research aims at developing a new plant growth inhibitors related to abscisic acid by means of esterification of (S)-(+)-ABA with p-hydroxy methyl cinnamate and umbelliferone, and testing its biological activity on growth of rice seedlings. The over-all yield of ABA-methyl cinnamate(AC) and ABA-umbelliferone(AC) ester compounds were 83% and 78%, respectively. The growth inhibition activity of these synthetic compounds were shown about 3 to 10 times(AC) and 10 to 30 times(AU) higher than (S)-(+)-ABA.