방사선조사가 백서 법랑질형성 과정에 미치는 영향에 관한 연구

RADIATION EFFECT ON THE STAGES OF AMELOGENESIS IN THE RAT INCISOR

  • 최현배 (서울대학교 치과대학 구강악안면방사선학 교실) ;
  • 최순철 (서울대학교 치과대학 구강악안면방사선학 교실) ;
  • 박태원 (서울대학교 치과대학 구강악안면방사선학 교실) ;
  • 유동수 (서울대학교 치과대학 구강악안면방사선학 교실)
  • Choi Hyun-Bae (Department of Oral and Maxillofacial Radiology, College of Dentisty, Seoul National University) ;
  • Choi Soon-Chul (Department of Oral and Maxillofacial Radiology, College of Dentisty, Seoul National University) ;
  • Park Tae-Won (Department of Oral and Maxillofacial Radiology, College of Dentisty, Seoul National University) ;
  • You Dong-Soo (Department of Oral and Maxillofacial Radiology, College of Dentisty, Seoul National University)
  • 발행 : 1997.02.01

초록

The purpose of this study was to investigate the radiation effect on the stages of amelogenesis. Twenty ll-day-old rats which were irradiated by 4Gy of garmna radiation on the 19th prenatal day were used for the experimental group and twenty ll-day-old rats which were not irradiated were used for the control group. The length of each zone of amelogenesis were measured on the sagittal section using a light microscopic enlargement at 400 x the normal view while the morphologic changes of ameloblasts of each zone were observed electron­microscopically. The obtained results were as followed : 1. The length of the region of facing pulp and facing dentin of the zone of presecretion were increased by 11.5%(P<0.05) and 17.7%(P<0.01), respectively. 2. The length of the zone of secretion was increased by 17.3%(P<0.01), but the zone of maturation was decreased by 15.3%(P<0.01). 3. The total length of the zone of amelogenesis was not changed significantly(P>0.05). 4. Electron-microscopically, enlargement of the cell membrane, rER, mitochondria, and nuclear membrane were observed. These changes were mostly severe in the zone of maturation.

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