한국전문물리치료학회지 (Physical Therapy Korea)
- 제4권1호
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- Pages.11-19
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- 1997
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- 1225-8962(pISSN)
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- 2287-982X(eISSN)
초음파치료가 종양세포에 미치는 효과
Effects of Continuous Therapeutic Ultrasound on Subcutaneous Murine Melanoma
- Kim, Ji-Won (Dept. of Rehabilitation, The Graduate School, Yonsei University) ;
- Lee, Kuk-Il (Dept. of Rehabilitation, College of Health Science, Yonsei University) ;
- Han, Jae-Mun (Dept. of Rehabilitation, College of Health Science, Yonsei University)
- 발행 : 1997.05.10
초록
The use of therapeutic ultrasound(US) in humans with malignant neoplasms has been contraindicated in physical therapy practice. Some studies have shown that results after application of US differ according to tumor type and penetration depth. The purposes of this study were to determine the effects of US on melanoma in mice and to determine treatment dosage. Twenty-four female C57BL/6 mice, age 8 weeks. The right flank of all mice was shaved, and a 0.1 ml suspension of cells was injected subcutaneously into the animals' right flank. In this study, 24 subjects were randomly divided into three groups: experimental group 1(n=8), experimental group 2(n=8), control group(n=8). In the experimental group 1, animals received continuous 3 MHZ US treatment, administered at