개에서 시행한 한쪽 이식 폐의 $^{99m}TC-MAA$ 관류스캔

$^{99m}TC-MAA$ Pulmonary Perfusion Scan in the Canine Single Luhg Transplant

  • 전석길 (계명대학교의과대학 핵의학교실) ;
  • 류종걸 (계명대학교의과대학 핵의학교실) ;
  • 박창권 (계명대학교의과대학 흉부외과학교실) ;
  • 유영선 (계명대학교의과대학 흉부외과학교실) ;
  • 정덕수 (대구가톨릭대학병원 방사선과) ;
  • 이종길 (대구파티마병원 방사선과)
  • Zeon, S.K. (Department of Nuclear Medicine, Keimyung University, School of Medicine) ;
  • Ryu, J.G. (Department of Nuclear Medicine, Keimyung University, School of Medicine) ;
  • Park, C.K. (Department of Thoracic and Cardiovascular Surgery, Keimyung University, School of Medicine) ;
  • Yoo, Y.S. (Department of Thoracic and Cardiovascular Surgery, Keimyung University, School of Medicine) ;
  • Jung, D.S. (Department of Radiology, Taegu Catholoc University Hospital) ;
  • Lee, J.K. (Department of Radiology, Taegu Fatima Hospital)
  • 발행 : 1997.09.30

초록

The aim of this study is to evaluate the efficiency of the pulmonary perfusion scan(Pp scan) in the experimental animal single lung transplantation. Eight left lung transplanted mongrel dogs were included in this study. The serial Pp scan with 111MBq $^{99m}TC-MAA$ were done at the periods of immediate postoperative period, POD 3 days, and POD 10-14 days and finally autopsy was done in each cases. The transplanted lung perfusion was analysed as a percentage radioactivity of trans planted/native lung(T/N) ratio. The Pp scan of a donor mongrel dog was used as a reference(left/right lung (T/N) ratio 85.2%). The average T/N ratio of all cases on immediate postoperative state(reperfusion injury) : 19.2%, three acute rejections. 12.6%, three bronchial dehiscences 6.1% and two pulmonary thromboses : 2.0%. Two cases showed moderate improvement of reperfusion injury as increasing the T/N ratio in POD 3 days Pp scan. The T/N ratio showed sequentially decreased in six cases. As a conclusion, the Pp scan could be a non-invasive method in the evaluation of the experimental one-lung transplanted mongrel dog.

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