Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
권호 표지
DOI QR코드

DOI QR Code

Effect of Glycerophospholipid on Oleate-Dependent Phospholipase D in Mammalian Source

  • Published : 1997.11.20
Download PDF
⟨ Previous Next ⟩

Abstract

Effects of exogenous glycerophospholipids on oleate-dependent phospholipase D (PLD) activity were studied in lymphocytic mouse leukemia L1210 cells and in solubilized microsomal phospholipase D of rat brain. Among the phospholipids tested phosphatidic acid had the most stimulatory effects on both PLD activities up to about 3 folds. Lysophosphatidic acid also showed promoting effect on microsomal PLD activity but much less on L1210 cells compared to that of phosphatidic acid. While phosphatidylethanolamine increased PLD activity slightly, phosphatidylinositides were nearly ineffective in the tested sources. The stimulatory effect of phosphatidic acid observed can be utilized to improve the in vitro assay system for oleate-dependent PLD in mammalian sources.

Keywords

References

  1. Can. J. Biochem. v.58 Chalifour, R. J.;Taki, T.;Kanfer, J. N.
  2. J. Biol. Chem. v.272 Exton, J. H.
  3. Biochem. J. v.281 Van Corven, E. J.;Van Rijswijk, A.;Jalink, K.;Van der Bend, R. L.;Van Blitterswijk, W. J.;Moolenar, W. H.
  4. Biochem. J. v.247 Altin, J. G.;Bygrave, F. L.
  5. Arch. Biochem. Biophys. v.283 Metz, S. A.;Dunlop, M.
  6. J. Biol. Chem. v.267 Moritz, A.;DeGraan, P. N. E.;Gispen, W. H.;Wirtz, K. W. A.
  7. FEBS Lett. v.323 Sato, T.;Ishimoto, T.;Akiba, S.;Fuji, T.
  8. Biochem. Soc. Trans. v.86 Wakelame, M. J. O.;Briscoe, C. P.;Stewart, A.;Pettitt, T. R.;Cross, M. J.;Paul, A.;Yule, J. M.;Gardner, S. D.;Hodgkin, M.
  9. J. Biochem. v.15 Zaman, W.;Mituyama, T.;Hatakenaka, M.;Kang, D.;Minakami, S.;Tageshige, K.
  10. Chem. Phys. Lipids v.80 English, D.;Cui, Y.;Siddiqui, R. A.
  11. Curr. Biol. v.7 Colley, W. C.;Sung, T.;Roll, R.;Jenco, J.;Hammond, S. M.;Altshuller, Y.;Bar-Sagi, D.;Morris, A. J.;Frohman, M. A.
  12. Proc. Natl. Acad. Sci. U. S. A. v.91 Massenburg, D.;Han, J.;Liyanage, M.;Patton, W. A.;Rhee, S. G.;Moss, J.;Vaughan, M.
  13. J. Biol. Chem. v.269 Okamura, S.;Yamashita, S.
  14. Chem. Phys. Lipids v.80 Liscovitch, M.;Chalifa-Caspi, V.
  15. Bull. Korean Chem. Soc. v.10 Jung, K.;Koh, E.;Choi, M.
  16. Ph. D. Thesis, Seoul National University Partial purifieation and characterization of phospholipase D from rat brain Kim, B. S.
  17. J. Biol. Chem. v.254 Taki, T.;Kanfer, J. N.
  18. Biochem. J. v.292 Dubyak, G. R.;Schomisch, S. J.;Kusner, D. J.;Xie, M.
  19. J. Biol. Chem. v.270 Yeo, E.;Exton, J. H.
  20. J. Neurochem. v.39 Chalifour, R.;Kanfer, J. N.
  21. J. Biol. Chem. v.269 Gomez-Munoz, A.;Martin, A.;O'Brien, L.;Brindly, D. N.
  22. Biochem. Biophhys. Acta v.1198 Jalink, K.;Hordijk, P. L.;Moolenaar, W. H.
  23. FEBS. Lett. v.383 Kanfer, J. N.;McCartney, D. G.;Singh, I. N.;Freysz, L.
  24. J. Biol. Chem. v.271 Bogdanov, M.;Sun, J.;Kaback, H. R.;Dowhan, W.
  25. J. Cell Biol. v.136 Chernomordik, L. V.;Leikina, E.;Frolov, V.;Bronk, P.;Zimmerberg, J.
  26. Science v.274 Song, L.;Hobaugh, M. R.;Shustak, C.;Cheley, S.;Bayley, H.;Gouaux, J. E.
  27. J. Biol. Chem. v.271 Ghosh, S.;Strum, J. C.;Sciorra, V. A.;Daniel, L.;Bell, R. M.