Journal of Microbiology and Biotechnology
- Volume 7 Issue 5
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- Pages.318-322
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- 1997
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- 1017-7825(pISSN)
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- 1738-8872(eISSN)
Optimal Resolution of L-Carnitine from Racemic DL-Carnitine by Enterobacter sp. Assimilating D-Carnitine
- Hwang, Ki-Chul (Department of Agricultural Chemistry, Korea University) ;
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Bang, Won-Gi
(Department of Agricultural Chemistry, Korea University)
- Published : 1997.10.01
Abstract
In order to isolate a microorganism having preferential degradation of D-carnitine from DL-carnitine, a bacterium assimilating D-carnitine as a sole carbon and energy source was isolated from soil by enrichment culture and partially identified as Enterobacter sp. Also, a mutant having lessened L-carnitine decomposition rates was selected with nitrosoguanidine mutagenesis, which led to decrease the specific activities of carnitine dehydrogenase (7.6-fold) and