식물조직배양학회지 (Korean Journal of Plant Tissue Culture)

한국식물생명공학회 (The Korean Society of Plant Biotechnology)
권호 표지

Matrix Attachment Regions (MARs) as a Transformation Booster in Recalcitrant Plant Species

  • 발행 : 1997.07.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

For genetic engineering to be commercially viable, an efficient transformation system is needed to produce transgenic plane from diverse genotypes ("generalized protocol"). Development of such a system requires optimization of a number of components such as gene transfer agent, plant tissues competent for both regeneration and transformation, and control of transgene expression. Although several novel gene transfer methods have been developed for plane, a majority of stably transformed plane express the introduced genes at low levels. Moreover, silencing of selectable marker genes shortly after their incorporation into plant chromosomes may result in low recovery of transgenic tissues from selection. Matrix attachment regions (MARs) are DNA sequences that bind to the cell's proteinaceous nuclear matrix to form DNA loop domains. MARs have been shown to increase transgene expression in tobacco cells, and reduce position in mature transgenic plants. Flanking an antibiotic resistance transgene with MARs should therefore lead to improved rates of transformation in a diversity of species, and may permit recalcitrant species and genotypes to be successfully transformed. Literature review and recent data from my laboratory suggest that MARs can serve as a transformation booster in recalcitrant plant species.

키워드

참고문헌

  1. Plant Cell v.8 High-level transgene expression in plant cells: Effects of a strong scaffold attachment region from tobacco Allen GC;Hall GJr;Michalowski S;Newman W;Spiker S;Weissinger AK;Thompson WF
  2. Plant Cell v.5 Scaffold attachment regions increase reporter gene expression in stably transformed plant cells Allen GC;Hall GE;Childs LC;Weissinger AK;Spiker S;Thompson WF
  3. Mol Cell Biol v.10 Expression of a foreign gene in a line of transgenic mice is modulated by a chromosomal position effect Al-Shaw R;Kinnaird J;Burke J;Bishop JO
  4. Mol Cell Biol v.10 Drosophila scaffold-attachment regions bind nuclear scaffolds and can function as ARS element in both budding and fission yeasts Ammati BB;Gasser SM
  5. Nucleic Acids Research v.21 Detection, sequence patterns, and function of unusual DNA structures Anderson JN
  6. Plant Physiol v.99 DNA methylation is involved in maintenance of an unusual expression pattern of an introduced gene Bochardt A;Hodal L;Palmgren G;Mattsson O;Okkels FT
  7. Plant Cell v.6 Distinct phenotypes generated by overexpression and suppression of S-adenosyl-L-methionine synthetase reveal developmental patterns of gene silencing in tobacco Boerjan W;Bauw G;Van Montagu M;Inze D
  8. Bio/Technology v.13 Instability of transgene expression in field grown tobacco carrying the csr1-1 gene for sulfonylurea herbicide resistance Brandle JE;McHugh SG;James L;Labbe H;Miki BL
  9. Transgenic Research v.3 The role of scaffold attachment regions in the structural and functional organization of plant chromatin Breyne P;Montagu M;Gheysen G
  10. Plant Cell v.4 Characterization of a plant scaffold attachment regions in a DNA fragment that normalize transgene expression in tobacco Breyne P;Montagu Mv;Depicker A;Gheysen G
  11. Mol Gen Genet v.243 Molecular analysis of transgenic plants generated by microprojectile bombardment: effect of petunia transformation booster sequence Buising CM;Benbow RM
  12. FEBS Lett v.204 Chromosomal loop anchorage sites appear to be evolutionary conserved Cockerill PN;Garrard WT
  13. Nucleic Acids Research v.15 Sequence and centromere proximal location of a transformation-enhancing fragment ans1 from Aspergillus nidulans Cullen D;Wilson LJ;Grey GL;Henner DJ;Turner G;Ballance DJ
  14. Euphytica v.71 The cell biology of plant transformation: current state, problems, prospects and the implications for the plant breeding De Block M
  15. Cell v.44 Structure of the 30 nm chromatin fiber Felsenfeld G;McGhee JD
  16. Bio/Technology v.12 Transgene inactivation: plants fight back! Finnegan J;McElroy D
  17. Proc Natl Acad Sci U S A v.91 Inactivation of gene expression in plants as a consequence of specific sequence duplication Flavell RB
  18. Mol Gen Genet v.247 The transformation booster sequence from Petunia hybrida is a retrotransposon derivative that binds to the nuclear scaffold Galliano H;Muller AE;Lucht JM;Meyer P
  19. Plant J v.6 The B-phaseolin gene is flanked by matrix attachment regions Geest AHM;Hall GEJ; Spiker S;Hall T
  20. Plant Mol Biol v.23 Singlecopy T-DNA insertions in Arabidopsis are the predominant form of integration in root-derived transgenics, whereas multiple insertions are found in leaf discs Grevelding C;Fantes V;Kemper E;Schell J;Masterson R
  21. Cell v.51 Position-independent, high-level expression of the human B-Globin gene in transgenic mice Grosveld F;Assendelft BG;Greaves DR;Kollias G
  22. Proc Natl Acad Sci USA v.88 Nuclear scaffolds and scaffold-attachment regions in higher plants Hall GJr;Allen GC;Loer DS;Thompson WF;Spiker S
  23. Forest Genetics v.1 Adventitious root and shoot regeneration In vitro in under major gene control in an F2 family of hybrid poplar(Populus trichocarpa × P. deltoides) Han KH;Bradshaw HD;Gordon MP
  24. Biology of Populus and its implication for management and conservation Cellular and molecular biology of Agrobacterium-mediated transformation of plants and its application to genetic transformation of Populus Han KH;Gordon MP;Strauss SH;Stettler Jr HDB RF(ed.);Heilman PE(ed.);Hinckley TM(ed.)
  25. Canadian Journal Forest Research High frequency transformation of cottonwoods (genus Populus) by Agrobacterium rhizogenes Han KH;Gordon MP;Strauss SH
  26. Transgenic Research Matrix attachment regions enhance transgene expression and transformation in poplar Han KH;Ma C;Strauss SH
  27. Plant J v.6 Efficient transformation of rice(Oryza sativa L.) meiated by Agrobacterium and sequence analysis of the boundaries of the T-DNA Hiei Y;Ohta S;Komari T;Kumashiro T
  28. Plant Mol Biol v.21 Transgene copy number can be positively or negatively associated with transgene expression Hobbs SLA;Warkentin TD;DeLong CMO
  29. Cell v.57 RAP-1 factor is necessary for DNA loop formation In vitro ata the silent mating type locus HML Hoffman JEX;Laroche T;Brand AH;Gasser SM
  30. Plant Mol Biol v.22 A poplar tree proteinase inhibitor-like gene promoter is responsive to wounding in transgenic tobacco Hollick JB;Gordon MP
  31. Chromosoma v.98 Bent DNA is a structural feature of scaffold-attached regions in Drosohila melanogaster interphase nuclei Homberger HP
  32. Ann Sci For v.50 Genetic transformation: A short review of methods and their applications, results and perspectives for forest trees Jouanin L;Brasileiro ACM;Leple JC;Pilate G;Cornu D
  33. Plant Science v.67 Molecular analysis of transgenic plants derived from transformation of protoplasts at various stage of the cell cycle Kartzke S;Saedler H;Meyer P
  34. Biochemistry v.30 Scaffold-attached regions from the human interferon B domain can be used to enhance the stable expression of genes under the control of various promoters Klehr D;Maass K;Bode J
  35. Plant J v.3 Characterization and mapping of a gene controlling shoot regeneration in tomato Koomneef M;Bade J;Hanhart C;Horsman K;Schell J;Soppe W;Verkerk R;Zabel P
  36. Curr Opion Genet Dev v.2 Scaffold-associated regions: cis-acting determinants of chromatin structural loops and functional domains Laemmli UK;Kas E;Poljak L;Adachi Y
  37. Theo Appl Genet v.78 Effect of repeated DNA sequences on direct gene transfer in protoplast of Nicotiana plumbaginifolia Marchesi ML;Castiglione S;Sala F
  38. Plant Physiol v.107 How and why do plants inactivate homologous (trans)genes? Matzke MA;Matzke JM
  39. EMBO J v.8 Reversible methylation and inactivation of marker genes in sequentially transformed tobacco plants Matzke MA;Priming M;Trnovsky J;Matzke AJM
  40. Ann Rev Biochem v.59 Nucleosome structure McGhee JD;Felsenfeld G
  41. Biochemistry v.29 Hierarchical binding of DNA fragments derived from scaffold-attached regions: correlation of properties In vitro and function in vivo Meilke C;Kohwi Y;Kohwi-Shigematsu Y;Bode J
  42. Proc Natl Acad Sci USA v.85 A genomic DNA segment from Petunia hybrida leads to increased transformation frequencies and simple integration patterns Meyer P;Kartzke S;Niedenhof I;Heidmann I;Bussman K;Saedler H
  43. Ann Rev Plant Physiol Plant Mol Biol v.47 Homology-dependent gene silencing in plants Meyer P;Saedler H
  44. Plant Cell v.7 The MAR-mediated reduction in position effect can be uncoupled from copy number-dependent expression in transgenic plants Mlynarova L;Jansen RC;Conner AJ;Stiekema WJ;Nap JP
  45. Plant Cell v.6 Reduced position effect in mature transgenic plants conferred by the chicken lysozyme matrix-associated region Mlynarova L;Loonen A;Heldens J;Jansen RC;Keizer P;Stiekema WJ;Nap JP
  46. Plant Cell v.7 The MAR-mediated reduction in position effect can be uncoupled from copy number-dependent expression in transgenic plants Mlynarova L;Jansen RC;Conner AJ;Stiekema WJ;Nap JP
  47. Plant Cell v.8 Approaching the lower limits of transgene variability Mylnarova L;Keizer LCP;Stiekema WJ;Nap JP
  48. Plant Cell v.2 Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous gene in trans Napoli C;Lemieux C;Jorgensen R
  49. Plant Molecular Biology v.21 Treatment of Agrobacterium or leaf disks with 5-azacytidine increases transgene expression in tobacco Palmgren G;Mattson O;Okkels FT
  50. Chromosome and chromatin structure Scaffolding and radial loops: the structural organization of metaphase chromosomes Paulson, JR;K. W. Adolph(ed.)Boca Raton, FI(ed.)
  51. Plant Mol Biol v.17 Transgene expression variability (position effect) of CAT and GUS reporter gene driven by linked divergent T-DNA promoters Peach C;Velten J
  52. EMBO J v.7 The matrix attachment regions of the chicken lysozyme gene co-map with the boundaries of the chromatin domatin Phi-Van L;Stratling WH
  53. Phytopathology v.80 Susceptibility of intra-and inter-specific hybrid poplars to Agrobacterium tumefaciens strain C58 Riemenschneider DE
  54. Transgenic Research v.2 An SAR sequence containing 395 bp DNA fragment mediates enhanced, gene-dosage-correlated expression of a chimaeric heat shock gene in transgenic tobacco plants Schoffl F;Schroder G;Kliem M;Rieping M
  55. J Cell Biochem v.21B Nuclear matrix attachment regions (MARs) in plants: affinity for the nuclear matrix and effect on transient and stable gene expression Spiker S;Allen GC;Hall GEJ;Michalowski S;Newman W; Thompson W;Weissinger AK
  56. Plant Physiol v.110 Nuclear matrix attachment regions and transgene expression in plants Spiker S;Thompson WF
  57. EMBO J v.9 In vitro DNA methylation inhibits gene expression in transgenic tobacco Weber H;Ziechmann C;Graessmann A