Environmental Analysis Health and Toxicology

The Korean Society of Environmental Health and Toxicology (환경독성보건학회)
권호 표지

The Effect of Sulfur Dioxide by Burn out on Enzyme Activity and Lipid Content in Rats

소환시 발생되는 아황산 가스가 흰쥐 혈청 중의 효소 활성도 및 지질 함량에 미치는 영향

  • Kim, Hae-Dong (Yeungnam University, Graduate School of Environmental studies) ;
  • Kim, Byung-Hak (Catholic University of Taegu Hyosung Dept. of Pharmacy) ;
  • Ha, Hun (Taegu Polytechnic College) ;
  • Cho, Soo-Yeul (Yeungnam University, Dept. of Food and Nutrition) ;
  • Yoon, Soo-Hong (Catholic University of Taegu Hyosung Dept. of Pharmacy)
  • 김해동 (영남대학교 환경대학원) ;
  • 김병학 (대구효성카톨릭대학교 약학과) ;
  • 하헌 (대구산업전문대학 식품가공학과) ;
  • 조수열 (영남대학교 식품영양학과) ;
  • 윤수홍 (대구효성카톨릭대학교 약학과)
  • Published : 1997.10.01
Download PDF
⟨ Previous Next ⟩

Abstract

Recently, incidences of pulmonary-related diseases are increasing and natural ecosystem is destroyed year by year owing to air pollutions by industrial noxious gases such as sulfur dioxide and carbon dioxide, etc. Sulfur dioxide produced by oxidation of sulfur compounds is water soluble and causes several kinds of pulmonary diseases, damaging on plants and animals. This study was undertaken to investigate effects of acute exposure of rats to sulfur dioxide using biochemical parameters. The sAST (aspartate transaminase) activity was not significantly affected but sALT (alanine transaminase), sLDH (lactate dehydrogenase) and sALP (alkaline phosphatase) activities were significantly increased by acute sulfur dioxide gas exposure. Also sulfur dioxide gas treatment significantly diminished serum cholinesterase activity. The total lipid, triglyceride, total-, HDL- and LDL-cholesterol contents were significantly increased by sulfur dioxide gas exposures. But the body and liver weight were generally diminished in comparison with control group. Our results' showed increased enzyme activities and lipid contents, but body and liver weight were all diminished by sulfur dioxide gas treatment.

Keywords