Journal of the Korean Magnetic Resonance Society (한국자기공명학회논문지)
- Volume 1 Issue 2
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- Pages.63-70
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- 1997
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- 1226-6531(pISSN)
Conformational Study of Decamer DNA Duplex $d(ACGTATACGT)_2$ by NMR Spectroscopy
- Lee, Joon-Hwa (Department of Chemistry, Korea Advanced Institute of Science and Technology) ;
- Park, Jin-Young (Department of Chemistry, Korea Advanced Institute of Science and Technology) ;
- Han, Hi-Jung (Department of Chemistry, Korea Advanced Institute of Science and Technology) ;
- Park, Byong-Seok (Department of Chemistry, Korea Advanced Institute of Science and Technology)
- Published : 1997.12.01
Abstract
The conformation of the self-complementary decamer duplex, d(ACGTATACGT)2 (TATA-duplex) has been studied by proton NMR spectroscopy. The duplex is essentially B-type, with distortions apparent at the TATA steps. These conformational distortion which may be preferable to occur in the thymine residue on the 5'-side, has been investigated by unusual NOE crosspeaks.
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