Effect of Artemisia Princeps Var Orientalis and Circium Japonicum Var Ussuriense on Serum Lipid of Hyprlipidemic Rat

쑥 및 엉겅퀴가 식이성 고지혈증 흰쥐의 혈청 지질에 미치는 영향

  • 임상선 (경상대학교 식품영양학과)
  • Published : 1997.02.01

Abstract

The effects of Artemisia princeps var orientalis(mugwort), Circium japonicum var ussuriense(Unggungqui) on serum lipid componets in rats was evaluated. Thirty rats divided into 5 experimental groups were fed with the diet containing 1% cholesterol, 0.25% sodium cholate, 10% coconut oil and 5% lard(control diet), supplemetned with 5% plant powder or its water soluble extract(experimental diet) for 4 weeks. Proximate analysis data and compositions of ash, dietary fiber and fatty acids in plants were presented. The concentrations of the total cholesterol was significantly lower in Ungungqui powder, Ungungqui extract and mugwort powder diet groups than the control. Serum HDL-cholesterol level was significantly higher in Unggunqui powder and Unggunqui extract diet group than the control. The concentration of LDL was significantly lower in Unggungqui power or extract diet group compared to the control. The values of VLDL and chylomicron were comparatively lower in Unggungqui power and mugwort powder diet group than in the other diet groups. The concentration of seum triglyceride and phospholipid was lower in Unggungqui powder diet group than in the control.

Keywords

References

  1. Introduction to risk factors in coronart artery disease in medical communication Stamler,J.
  2. 한국영양학회지 v.23 no.3 영양과 관련된 질환의 현황과 대책 허갑범
  3. 한국영양학회지 v.21 no.3 최근 우리나라에서의 질병변천 최강원
  4. Circulation v.85 Joint effects of serum troglyceride and LDL-cholesterol and HDL-cholesterol concentration on coronary heart disease risk in the helsinki heart study Manninen,V.;Tenkanen,L.;Kostinen,P.;Huttunen,T.K.;Manttari,M.;Heinonen,O.P.;Frick,H.M.
  5. J. Nutr. v.116 Diet, plasma cholesteral and coronary heart disease Rifkind,B.M.
  6. Am. J. Clin. Nutr. v.52 Oat-bran cereal lowers serum total and LDL-cholesterol in hypercholesterolemic men Anderson,J.W.;Spencer,D.B.;Hamilton,C.C.
  7. Arterosclerosis v.9 Dietary fish oil increases the conversion of VLDL apoB to LDL apoB Huff,M.W.;Telford,D.E.
  8. 日本營養食糧學會誌 v.37 no.4 ラツトの 食餌性 コしス テロ血症に 及しはナスヒルリナの影響 加藤敏光;竹本和夫;片山搏雄;矮原祥子
  9. 國擇 增補 東醫寶鑑 許俊
  10. 韓國産菊花科 植物에 對한 本草學的 硏究 朱榮丞
  11. 韓國植物大寶鑑 (下卷) v.1 송주택
  12. J. Ethnopharmacology v.26 Pharmacological screening and antimicrobial activity of the essential oil of artemisia caerulescens subsp. gallica Moran,A.;Montero,M.J.;Martin,M.L.;San,Roman,L.
  13. J. Pharmacol v.31 Choleretic effect of artemisia capillaris extract in rats Okuno,I.;Uchida,K.;Kaolowaki,M.;Akahori,A.
  14. Chem. Pharm. Bull. v.23 Capillarisin, a constituent from Artemisia capillaris Herba Komiya,T.;Sukui,M.T.;Oshio,H.
  15. J. Ethnopharmacology v.24 Hypoglycemic activity of Artemisia herba alba Twaij,H.A.;Badr,A.A.
  16. Chem. Pharm. Bull. v.33 no.5 Studies on the activities of tannins and related compounds from medicinal plants and drug Ⅶ. Effects of extracts of leaves of Artemisia, Species and caffeic acid and chlorogenic acid on lipid metabolic injury in rats fed peroxidized oil Kimura,Y.;Okuda,H.;Okuda,T.;Hatano,T.;Agata,I.;Arichi,S.
  17. 104th Annual meeting of the Pharmaceutical society of Japan Abstracts of paper Okuda,T.;Hatano,T.;Katayama,M.;Agata,I.;Nishibe,S.;Kimura,K.
  18. 한국영양식량학회지 v.21 no.1 쑥(산쑥)의 물 抽出物과 에테르 抽出物의 抗酸化 效果 이기동;김정숙;배재오;윤형식
  19. 中藥大辭典 小學館
  20. Cereal chemistry v.56 no.5 Mongeau,R.;R.Brassard
  21. Dietary fiber-basic and clinical aspects Plenum Southgate DAT
  22. J. Nutr. v.122 Soluble dietary fiber and cholesterol influence in vivo hepatic and intestinal cholesterol biosynthesis in rats Arjmandi,B.H.;Craig,J.;Nathani,S.;Reeves,B.D.
  23. J. Nutr. v.122 Dietary soluble fiber and cholesterol affect serum cholesterol concentration, hepatic portal venous short-chain fatty acid concentration and fecal sterol excretion in rats Arjmandi,B.H.;Ahn,J.;Nathani,S.;Reeves,R.D.
  24. 韓方醫學 大辭典 Ⅲ(中國藥學 大辭典) 陳存仁
  25. Am. J. Clin. Nutr. v.31 Fiber lipids and atherosclerosis Kritchevsky,D.
  26. J. Lipid Res. v.10 The interaction of cholesterol absorption and cholesterol synthesis in man Grundy,S.M.;Davignon,J.
  27. Adv. Lipid Res. The relationship between plasma and tissue lipid in human atherosclerosis Smith,E.B.
  28. JAMA v.264 no.23 Lipoproteins and atherogenesis Steinberg,D.;Witztum,J.L.
  29. Circulation v.85 no.6 Blood viscosity Lipoproteins and cardiovascular risk Lowe,G.D.O.
  30. Diabets and cardiovascular disease the Framingham study Kannel,W.B.;McGee,D.L.
  31. Am. Intern Med. v.86 Decrease in postprandial insulin and glucose concentration by guar and pectin Jenkins,D.J.A.;Gassull,M.A.;Cocher,B.;Alberti,K.G.
  32. Am. J. Clin. Nutr. v.56 McCall,M.R.;Mehta,T.;Lesathers,C.W.;Foster,D.M.
  33. J. Nutr. v.49 Wheat bran and wheat germ : effect on digestion and intestinal absorption of dietary lipids in the rat Borel,P.;Lair,D.;Senft,M.;Chautan,M.;Lafont,H.
  34. Am. J. Clin. Nutr. v.45 Dietary fiber and lipids Miettinen,T.A.
  35. Am. J. Clin. Nutr. v.55 Effect of oat bran, rice bran, wheat fiber and wheat germ on postprandial lipemia in gealthy adults Cara,L.;Dubois,C.;Borel,P.;Armand,M.;Senft,M.;Portugal,H.;Pauli,A.M.;Bernard,P.M.;Lairon,D.
  36. J. Nutr. v.118 Effect of dietary cholesterol and w1 or w3 fatty acids on lipid conposition and (△$^5$-desaturase activity or rat liver microsomes Garg,M.L.;Thomson,B.R.
  37. Nutr. Rep. Int. v.24 Effects of oat bran, oat gum and pectin on lipid metabolism of cholesterol fed rats Chen,W.J.L.;Anderson,J.W.;Gould,M.R.
  38. J. Nutr. v.112 Effect of dietary fibers on lipid metabolism in liver and adpose tissue in chicks Akiba,Y.;T.Matsumoto