The Effects of Haepyoyijintang on The lnjured Tracheal Tissue lnduced $SO_{2}$ in Rats

해표이진탕이 $SO_{2}$에 의한 흰쥐의 호흡기조직 손상에 미치는 영향

  • Published : 1997.06.01

Abstract

This experiment was performed in order to study the effects of haepyoyijintang on the injured tracheal tissue induced $SO_{2}$ in rats. Healthy adult male rats weighting about 250g were divided into 4 groups-the Normal group, the Control group, the group of Haepyoyijintang administration for 5days after $SO_{2}$gas exposure (Sample I), and the group of Haepyoyijintang adiministration for 10 days before and for 5days after $SO_{2}$ gas exposure (Sample II). The results were obtained as follows; 1. In the trachea Control group, the lesion of the ciliated epithelium was and the mucus secretion of the respiratory tract was increased iginificantly. 2. In the trachea of SampleIgroup, the lesion of the ciliated epithelium and the mucus secretion of the respiratory tract were decreased compared with Control group. 3. In the trachea of SampleIIgroup, the lesion of the ciliated epithelium and the mucus secretion of the respiratory tract were decreased compared with Control and Sample Igroup. According to the above results, Haepyoyijintang has significant effects on the injuried tracheal tissu caused by $SO_{2}$ in rats.

Keywords

References

  1. 臨床呼吸器學 韓鏞徹
  2. 大氣汚染物質の動態 野謙治(編)
  3. 中國醫學史略 賣得道
  4. 解表二陳湯의 鎭痛 鎭痙 解熱 및 $O_3$ 中毒으로 인한 흰쥐의 肺損償에 미치는 影響 朴東一
  5. 濟衆新編 康明吉
  6. 晴崗醫鑑 金永勳
  7. 東醫寶鑑 許浚
  8. 方藥合編 黃度淵
  9. 解表二陳湯이 흰쥐의 $SO_2$에 의한 呼吸器損傷에 미치는 影響 李京泰
  10. 東醫肺系內科學 李衍九;鄭昇杞
  11. 呼吸器學 朴泰植
  12. 成人病豫防 및 管理 李文鎬
  13. 現代環境衛生學 朴良元;金亨錫
  14. 大氣汚染槪論 禹完基
  15. 內科學(下) 李文鎬;全鐘暉;許仁穆 (외)
  16. J. Toxicol. Clin. Toxicol. v.29 Air pollutants and the respirtory system, Toxicity and Phamacologic interventions Koenig, J. Q.;Pierson, W. E.
  17. Agents Actions v.26 Sulfur dioxide-induced airway hyperreactivity and pulmonary inflammation in dogs Norris, A. A.;Jackson, D. M.
  18. Japan J. Ind. Health v.4 no.22 The effect of sulfur dioxide upon mechanical properities of the lungs in dogs Yokoyama, E.;Ishkawa, K
  19. Proc. Roy. Soc. Med. v.57 Studies on the Effects of Acute Exposure to Sulfure Dioxide in human Subjects Frank, N. R.
  20. Int. J. Air water Pollution v.8 no.125 A Comparison of Effects of $SO_2$ Administred Alone or in Combination with NaCl Particles on Respiratory Mechanics of Healthy Audults Frank, N. R.;Amdur, M. O.;Whittenberger, J. L.
  21. J. Appl. Physiol. v.17 no.252 Effects of Acute Controlled Exposure to $SO_2$ on Respiratory Mechanics of Healthy in Healthy Male Adults Frank, N. R.;Amdur, M. O.;Worcester, J.;Whitten-berger, J. L.
  22. Brit. J. Ind. Med. v.23 no.75 A Comparison of Changes in Pulmonary Flow Resistance in Healthy Voluneers Acutely Exposed to $SO_2$ by Mouth and by Nose Frank, N. R.;Speizer, F. E.
  23. Arch. Environ. Health v.11 no.624 $SO_2$ Effects on the Respiratory System in Dogs Frank, N. R.;Speizer, F. E.
  24. J. Physol. v.7 no.132 Uptake and Release of $SO_2$ by the Human Nose Frank, N. R.;Speizer, F. E.
  25. J. Allergy. Clin. Immunol. v.76 The effects of sulfur oxides on nasal and lung function in adolescents with extrinsic asthma Koenig, J. Q.;Morgan, M. S.;Horike, M.;Pierson, W. E.
  26. Japan J. Ind. Health v.3 no.77 Effects of $SO_2$ on Human Pulmonary Functions Tomono, Y
  27. Arch. Environ. Health v.15 no.412 Mechnism of Respiratory Effects During Exposure of Guinea Pigs to Irritants Davis, T. R. A.;Battista, S. P.;Kensler, C. J.
  28. Proc. Roy. Soc. Med. v.57 Studies on the Effects of Acute Exposure to Sulfure Dioxide in human Subjects Frank, N. R.
  29. J. Allergy Clin. Immunol. v.79 The effects of albuterol on sulfur dioxide-induced bronchoconstriction in allergic adolescents Koenig, J. Q.;Marshall, S. G.;Horike M.;Shapiro, G. G.;Furukawa, C. T.;Bierman, C. W.;Pierson, W. E.
  30. Biomed. Pharm. v.44 Respiratory effects of pollution Philip Joet F
  31. J. Ind. Hyg. Toxicol v.4 no.193 The effect of Irritant Gases upon the Rate of Ciliary Activity Cralley, L. V.
  32. Bri. J. Ind. Med. v.13 no.110 Mucous Flow and Cilliary Activity in the Trachea of Rats Exposed to Pulmonary Irritant gas Dalhamn, T.;Rohdin, J.
  33. J. Appl. Physiol. v.20 no.164 Mechanism of Broncoconstriction During Inhalation of Sulfur Dioxide Nadel, J. A.;Salem, H.;Tamplin, B.;Tokwa, Y.
  34. J. Ind. Hyg. Toxicol. v.4 no.193 The effect of Irritant Gases upon the Rate of Ciliary Activity Cralley, L. V.
  35. The pathophysiology of bronchial mucus Ann. N. Y. Acad. Sc. v.106 Tappan, V.;Zalar, V.
  36. Brit. J. Prevent & Social Med. v.9 Mustard gas posisoning, chronic bronchitis and lung cancer Case, R. A. M.;A. J. Lea
  37. J. Nati. Cancer Inst. v.32 The effect of air pollutants on ciliated mucus secreting epithelium Tremer, H.;Falk and Kotin, P.;
  38. Cited from Ann. N. Y. Acad. Sc. v.106 The response of mucus secreting epithelium and mucus to irritants Falk;Hans L;Paul Kotin;Winifred Rowlette
  39. 臨床呼吸器學 韓鏞徹
  40. 카톨릭 醫學大學論文集 v.15 傷害가 呼吸器粘液分泌에 미치는 影響에 對한 自己放射法에 依한 觀察 徐鐸煥;金永濟
  41. Histopathology of the Ear, Nose and Throat Eggston, A. A.;Wolf, D.
  42. Ann. N. Y. Acad. Sc. v.106 The response of mucus secreting epithelium and mucus to irritants Falk, H. L.;Kotin, P.;Rowlette, W.
  43. 臨床呼吸器學 韓鏞徹
  44. 中國醫學史略 賣得道
  45. 解表二陳湯의 鎭痛 鎭痙 解熱 및 $O_3$ 中毒으로 인한 흰쥐의 肺損償에 미치는 影響 朴東一
  46. 濟衆新編 康明吉
  47. 晴崗醫鑑 金永勳
  48. 東醫寶鑑 許浚
  49. 方藥合編 黃度淵
  50. 解表二陳湯이 흰쥐의 $SO_2$에 의한 呼吸器損傷에 미치는 影響 李京泰
  51. 原色臨床本草學 辛民敎
  52. 本草學 李尙仁
  53. 中草藥學 海中醫學院(編)
  54. 本草綱目 李時珍
  55. 本經疏證 v.1 趨潤安