Archives of Pharmacal Research
- Volume 20 Issue 2
- /
- Pages.197-199
- /
- 1997
- /
- 0253-6269(pISSN)
- /
- 1976-3786(eISSN)
Synthesis of 1-(2-Naphthoyl) Benzotriazoles as Photoactivated DNA Cleaving Agents
- Yang, Jae-Wook (Department of Pharmacy, Sahmyook University) ;
- Wender, Paul-A. (Department of Chemistry, Stanford University)
- Published : 1997.04.01
Abstract
In conclusion, benzotriazole analogs prepared in this research showed strong possibility to be photochemically activated DNA cleaving agents. Electrophilic groups such as haloacetoxy groups on the alkyl chain of benzotriazole analogs promote the DNA cleaving ability. Synthesis of 1-(2-Naphthoyl) Benzotriazoles.