한국임상약학회지 (Korean Journal of Clinical Pharmacy)
- 제7권1호
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- Pages.17-21
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- 1997
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- 1226-6051(pISSN)
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- 2508-786X(eISSN)
세파클러 캅셀제에 대한 생물학적 동등성 평가
Bioequivalence of Cefaclor Capsules Following Single Dose Administration to Healthy Male Volunteers
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Bok, Hae Sook
(Department of Clincical Pharmacology, Samsung Biomedical Research Institute) ;
- Kim, Myoung Min (Department of Clincical Pharmacology, Samsung Biomedical Research Institute) ;
- Kwon, Yi Oh (Department of Clincical Pharmacology, Samsung Biomedical Research Institute) ;
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Choi, Kyung Eob
(Department of Clincical Pharmacology, Samsung Biomedical Research Institute, Division orf Parmaceutical Services. Samsung Medical Center)
- 발행 : 1997.05.01
초록
Cefaclor is a second generation cephalosporin antibiotic that shows a potent antibacterial activity against both Gram-positive and Gram-negative bacteria, when it is orally administered. Due to its patent expiration, a number of generic drugs have been marketed, but not yet elucidated to ensure therapeutic equivalence. In this study, cefaclor capsules manufactured by Chong Kun Dang were bioequivallently assessed by comparing with