Radiation Oncology Journal
- Volume 15 Issue 1
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- Pages.27-36
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- 1997
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- 2234-1900(pISSN)
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- 2234-3156(eISSN)
Concurrent Chemoradiation Therapy in Stage III Non-small Cell Lung Cancer
III 기 비소세포성 폐암에서 Cisplatin-방사선동시병합요법의 효과
- Kim In Ah (Departments of Radiation Oncology, St. Mays Hospital, Catholic University, Medical College Catholic Cancer Center) ;
- Choi Ihl Bhong (Departments of Radiation Oncology, St. Mays Hospital, Catholic University, Medical College Catholic Cancer Center) ;
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Kang Ki Mun
(Departments of Radiation Oncology, St. Mays Hospital, Catholic University, Medical College Catholic Cancer Center) ;
- Jang Jie Young (Departments of Radiation Oncology, St. Mays Hospital, Catholic University, Medical College Catholic Cancer Center) ;
- Song Jung Sub (Departments of Internal Medicine, St. Mays Hospital, Catholic University, Medical College Catholic Cancer Center) ;
-
Lee Sun Hee
(Departments of Thoracic Surgery, St. Mays Hospital, Catholic University, Medical College Catholic Cancer Center) ;
- Kuak Mun Sub (Departments of Thoracic Surgery, St. Mays Hospital, Catholic University, Medical College Catholic Cancer Center) ;
-
Shinn Kyung Sub
(Departments of Radiation Oncology, St. Mays Hospital, Catholic University, Medical College Catholic Cancer Center)
- 김인아 (가톨릭의대 성모병원 방사선 종양학과) ;
- 최일봉 (가톨릭의대 성모병원 방사선 종양학과) ;
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강기문
(가톨릭의대 성모병원 방사선 종양학과) ;
- 장지영 (가톨릭의대 성모병원 방사선 종양학과) ;
- 송정섭 (가톨릭의대 성모병원 내과) ;
-
이선희
(가톨릭의대 성모병원 흉부외과) ;
- 곽문섭 (가톨릭의대 성모병원 흉부외과) ;
-
신경섭
(가톨릭의대 성모병원 방사선 종양학과)
- Published : 1997.03.01
Abstract
Purpose : This study was tried to evaluate the Potential benefits of concurrent chemoradiation therapy (low dose daily cisplatin combined with split course radiation therapy) compared with conventional radiation therapy alone in stage III non-small cell lung cancer. The end points of analyses were response rate. overall survival, survival without locoregional failure, survival without distant metastasis, prognostic factors affecting survival and treatment related toxicities. Materials and Methods : Between April 1992 and March 1994, 32 patients who had stage III non-small cell lung cancer were treated with concurrent chemoradiation therapy. Radiation therapy for 2 weeks (300 cGy given 10 times up to 3000 cGy) followed by a 3 weeks rest period and then radiation therapy for 2 more weeks (250 cGy given 10 times up to 2500 cGy) was combined with
목적 : 국소진행된 III기 비소세포성 폐암에서 방사선감작제로서의 저용량 Cisplatin과 방사선 동시병합요법의 효과를 알아보고자하여, 관해율, 전체생존율, 무병생존율 및 치료에 따른 부작용을 방사선 단독치료군과 후향적으로 비교분석하였다. 대상 및 방법 : 1992년 4월부터 1994년 3월까지 32명의 III기 비세포성 폐암환자(IIIa 12명, IIIb 19명)가 항암제 및 방사선동시병합요법을 받았다. 방사선치료는 3000cZGy/10회를 2주간에 걸쳐 시행한 뒤 3주후에 2500cGy/10회를 추가하였으며, 방사선감작제로 ciplatin