The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
권호 표지

The effects of Ohwangsahwa-Tang(Wu-Huang-Xie-Huo-Tang) on Hypercholesterolemia Rats induced by 2% Chole- sterol Fed-Diet

콜레스테롤식(食) 유발(誘發) 고지혈증(高脂血症) 흰쥐에 대(對)한 오황석화탕(五黃瀉火湯)의 효과(效果)

  • Jang, Yong-Soo (Department of Circulatory Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Ko, Chang-Nam (Department of Circulatory Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Cho, Ki-Ho (Department of Circulatory Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Kim, Young-Suk (Department of Circulatory Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Bae, Hyung-Sup (Department of Circulatory Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Lee, Kyung-Sup (Department of Circulatory Internal Medicine, College of Oriental Medicine, Kyung Hee University)
  • 장용수 (경희대학교 한의과대학 심계내과학교실) ;
  • 고창남 (경희대학교 한의과대학 심계내과학교실) ;
  • 조기호 (경희대학교 한의과대학 심계내과학교실) ;
  • 김영석 (경희대학교 한의과대학 심계내과학교실) ;
  • 배형섭 (경희대학교 한의과대학 심계내과학교실) ;
  • 이경섭 (경희대학교 한의과대학 심계내과학교실)
  • Published : 1997.12.30
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Abstract

In order to study the effects of Ohwangsahwatang on Hyperchole-sterolemia, experimental study were performed on Hypercholesterolemia Rats induced by 2% cholesterol diet. Also the level of total cholesterol. triglyceride, LDL-cholesterol. HDL-cholesterol, phospholipid, transami-nase(GOT, GPT) were measured. The results were summerized as follows : In the model of Hypercholesterolemia induced by 2% cholesterol diet in rats, Ohwangsahwatang showed decreasing effects on total cholesterol, triglyceride, LDL-cholesterol, phospholipid level, and transaminase (GOT, GPT) activity in serum significantly, depending on the concentration, and showed increasing effects on HDL-cholesterol level in serum significantly depending on the concentration. According to the above results, Ohwangsahwatang showed significant decreasing effects on Hypercholesterolemia, and it is considered that it is appropriate to apply for Hypercholesterolemia.

Keywords

References

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