생약학회지 (Korean Journal of Pharmacognosy)
- 제28권4호
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- Pages.167-173
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- 1997
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
생약의 아세틸콜린에스터라제 억제활성 검색
Screening of the Acetylcholinesterase Inhibitors from Medicinal Plants
-
이봉호
(대전산업대학교 공업화학과)
;
- 유건식 (한국인삼연초연구소) ;
- 이은석 (대전산업대학교 공업화학과) ;
- 강기정 (대전산업대학교 공업화학과) ;
- 황도연 ((주) 한국신약) ;
- 홍남두 ((주) 한국신약) ;
-
최병욱
(대전산업대학교 공업화학과)
-
Lee, Bong-Ho
(Department of Industrial Chemistry, Taejon National University of Technology)
;
- Ryu, Geon-Seek (Korea Ginseng & Tobacco Research Institute) ;
- Lee, Eun Seog (Department of Industrial Chemistry, Taejon National University of Technology) ;
- Kang, Kye-Jung (Department of Industrial Chemistry, Taejon National University of Technology) ;
- Hwang, Dho-Yeun (Hankook Sin Yak Pharm. Co.) ;
- Hong, Nam-Doo (Hankook Sin Yak Pharm. Co.) ;
-
Choi, Byoung-Wook
(Department of Industrial Chemistry, Taejon National University of Technology)
- 발행 : 1997.12.30
초록
We have tested 101 species traditional medicinal plants on Acetylcholinester ase inhibition. Among them. Caesalpina sappan. Cnidium offcinale, Coptis japonica, Ephedra sinica, Eribotrya japonica, Gardenia jasminoides, Liriope platyphylla, Lonicera japonica, Paeonia suffruticosa, Phyllostachys nigra, Polygonum multiflorum, Prunella vulgaris, Rheum undulatum, Salvia miltiorrhiza and Uncaria rhynchophylla showed strong inhibition potency over 88%. In addition, Aconitum carmichaeli, Caesalphina sappan, Cinnamomun japonica, Citrus unshiu, Hordeum vulgare, Glycine max and Rehmannia glutinosa showed relatively good inhibition potency over 80%.