Korean Journal of Pharmacognosy (생약학회지)
- Volume 28 Issue 3
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- Pages.131-137
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- 1997
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Screening of Hyaluronidase Inhibitory Activity Using a Microplate Assay
Microplate방법을 이용한 Hyaluronidase 저해 활성 검색
- Jeong, Sei-Joon (College of Pharmacy, Wonkwang University) ;
- Kim, Na-Young (College of Pharmacy, Wonkwang University) ;
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Ahn, Nyeon-Hyoung
(College of Pharmacy, Wonkwang University)
;
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Kim, Youn-Chul
(College of Pharmacy, Wonkwang University)
- Published : 1997.09.30
Abstract
The aqueous and methanolic extracts of 110 crude drugs were screened for hyaluronidase inhibitory activity using a microplate assay. Among them, MeOH extract of 15 crude drugs inhibited more than 80% of hyauluronidase activity at the concentration of 5mg/ml. The active principles of Anemarrhenae Rhizoma, Rhei Rhizoma, Ephedrae Herba, Pteropi Faeces and Ginseng Radix alba were transferred into organic solvents.