The Korean Journal of Physiology and Pharmacology
- Volume 1 Issue 5
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- Pages.547-553
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- 1997
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- 1226-4512(pISSN)
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- 2093-3827(eISSN)
Role of Tyrosine Kinases in Vascular Contraction in Deoxycorticosterone Acetate-Salt Hypertensive Rats
- Yeum, Cheol-Ho (Department of Physiology, College of Medicine, Chosun University) ;
- Jun, Jae-Yeoul (Department of Physiology, College of Medicine, Chosun University) ;
- Choi, Hyo-Sub (Department of Physiology, College of Medicine, Chosun University)
- Published : 1997.10.21
Abstract
It has been known that activation of tyrosine kinases is involved in signal transduction. Role of the tyrosine kinase in vascular smooth muscle contraction was examined in deoxycorticosterone acetate (DOCA)-salt hypertensive rats. Male Sprague-Dawley rats underwent uninephrectomy, one week after which they were subcutaneously implanted with DOCA (200 mg/kg) and supplied with 1% NaCl and 0.2% KCl drinking water for
Keywords
- Tyrosine kinases;
- Vascular smooth muscle contraction;
- Deoxycorticosterone acetate-salt hypertensive rats