생물정신의학 (Korean Journal of Biological Psychiatry)
- 제3권1호
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- Pages.14-21
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- 1996
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- 1225-8709(pISSN)
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- 2005-7571(eISSN)
분자유전학을 통한 정신분열증의 이해
Understanding of Schizophrenia Based on the Study of Molecular Genetics
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Lee, Min-Soo
(Department of Psychiatry, Korea University College of Medicine) ;
- Kim, Pyo-Han (Department of Neuropsychiaty, Seoul Adventist Hospital)
- 발행 : 1996.06.30
초록
Molecular genetic approaches contribute to the understanding of the underlying genetic mechanism for schizophrenia. Currently genetic evidence rests on molecular genetic methods. However, the result are contradictory and somewhat confusing due to genetic heterogeneity, incomplete penetrance, misspecification of genetic model. It is expected that molecular genetics could provide key answers to the genetic cause of schizophrenia. The purpose of this article is to call attention of the readers to heterogeneity, linkage, association, basic molecular genetic methods and genetic markers and to the need far further research. It is the author's hope thai continuous research on the molecular genetics con provide clinicians with better understanding of the schizophrenia.