Tuberculosis and Respiratory Diseases
- Volume 43 Issue 4
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- Pages.623-629
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- 1996
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- 1738-3536(pISSN)
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- 2005-6184(eISSN)
A Case of Bronchopulmonary Atypical Carcinoid Tumor with Liver Metastasis
간전이를 동반한 폐기관지 비정형 카르시노이드 종양 1예
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Lee, Dong Soo
(Department of Internal Medicine, Catholic University Medical College) ;
- Lee, Tae Won (Department of Internal Medicine, Catholic University Medical College) ;
- Kim, Gye Yean (Department of Internal Medicine, Catholic University Medical College) ;
- Kim, Hwi Jung (Department of Internal Medicine, Catholic University Medical College) ;
- Song, So Hyang (Department of Internal Medicine, Catholic University Medical College) ;
- Kim, Seok Chan (Department of Internal Medicine, Catholic University Medical College) ;
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Kim, Young Kyoon
(Department of Internal Medicine, Catholic University Medical College) ;
- Song, Jung Sup (Department of Internal Medicine, Catholic University Medical College) ;
- Park, Sung Hak (Department of Internal Medicine, Catholic University Medical College)
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이동수
(가톨릭대학교 의과대학 내과학교실) ;
- 이태원 (가톨릭대학교 의과대학 내과학교실) ;
- 김지연 (가톨릭대학교 의과대학 내과학교실) ;
- 김휘정 (가톨릭대학교 의과대학 내과학교실) ;
- 송소향 (가톨릭대학교 의과대학 내과학교실) ;
- 김석찬 (가톨릭대학교 의과대학 내과학교실) ;
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김영균
(가톨릭대학교 의과대학 내과학교실) ;
- 송정섭 (가톨릭대학교 의과대학 내과학교실) ;
- 박성학 (가톨릭대학교 의과대학 내과학교실)
- Published : 1996.08.30
Abstract
Bronchial carcinoid tumors are uncommon, constituting approximately 5% of all primary lung cancers. Carcinoid tumors belong to the calss of neuroendocrine tumors that consist of cells that can store and secrete neuramines and neuropeptides. Neuroendocrine tumors of the lung include three pathologic types : a low-grade malignancy, the so-called 'typical carcinoid', a more aggressive tumor, the "atypical carcinoid", and the most aggressive malignant neoplasm, the small-cell carcinoma. Atypical carcinoid tumor have a higher malignant potential, is more commonly peripheral than is the typical carcinoid tumor. Histologic features would characterize a carcinoid as hitologically atypical : increased mitotic activity, pleomorphism and irregularity of neuclei with promonent nucleoli, hyperchromatin, and abnormal nuclear-cytoplasmic ratio, areas of increased cellularity with disorganization of architecture, and areas of tumor necrosis. Metastatic involvement of regional lymph nodes and distant organ is common. The prognosis is related to size of the tumor, typical of atypical appearance, endoluminal of extraluminal growth, vascular invasion, node metastasis, Pulmonary resection is the treatement of choice for bronchial carcinoid. We experienced one case of bronchopulmonary atypical carcinoid tumor. In the case, radiologic study showed solitary lung mass with liver metastasis and the level of 5-HIAA was elevated. There was no history of cutaneous flushing, diarrhea, valvular heart disease. The authors reported a case of bronchopulmonary atypical carcinoid tumor with review of literatures.
기관지 비정형 카르시노이드 종양은 임파절 및 다른 장기로의 전이율이 높은 질환으로 특별한 증상 없이 우연히 방사선학적 검사상 발견되어 지는 드문 질환으로 알려져 있으며, 수술적 절제술이 우선적 치료로 되어 있다. 저자들은 흥부 방사선적 검사 및 조직 검사로 진단되어 수술적 절제술을 시행한 간전이를 동반한 폐기관지 비정형 카르시노이드 종양 1예를 경험하였기에 보고한다.