The Korean Journal of Cytopathology (대한세포병리학회지)

The Korean Society for Cytopathology (대한세포병리학회)
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Fine Needle Aspiration Cytology of Angiosarcoma of the Rib - A Case Report -

늑골에 발생한 맥관육종의 세침흡인 세포학적 소견 - 1예 보고 -

  • Kim, Hee-Jung (Departments of Pathology, Yonsei University Wonju College of Medicine) ;
  • Cho, Mee-Yon (Departments of Pathology, Yonsei University Wonju College of Medicine) ;
  • Jung, Soon-Hee (Departments of Pathology, Yonsei University Wonju College of Medicine) ;
  • Lee, Kwang-Gil (Departments of Pathology, Yonsei University College of Medicine)
  • 김희정 (연세대학교 원주의과대학 병리학교실) ;
  • 조미연 (연세대학교 원주의과대학 병리학교실) ;
  • 정순희 (연세대학교 원주의과대학 병리학교실) ;
  • 이광길 (연세대학교 의과대학 병리학교실)
  • Published : 1996.12.30
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Abstract

Angiosarcoma of the bone is rare with an incidence of 0.13%. It may be solitary or multiple. Its cytologic findings by FNA have rarely been reported. We report a case of angiosarcoma of the rib in a 66 year-old man. FNA revealed single or clusters of round to oval shaped cells in a hemorrhagic and myxoid background. The large central nuclei had irregular nuclear membrane, chromatin clumping and prominent nucleoli. The cytoplasm was scanty with an eosinophilic distinct cytoplasmic border. Erythrophagocytosis by malignant cells was also found. Histopathologic examination confirmed the diagnosis of angiosarcoma revealing irregular and complex anastomosing vascular channels lined by malignant round tumor cells, protruding into the lumen. Immunohistochemical staining revealed diffuse strong positive reaction to factor VIII-related antigen and CD31.

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