Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Ruthenium Complex-Catalyzed Synthesis of Indoles from N-Substituted Anilines and Alkanolamines

  • Published : 1996.12.20
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Abstract

N-Substituted anilines react with triethanolamine at 180℃ in the presence of a catalytic amount of tris(triphenylphosphine)ruthenium(Ⅱ) chloride to give the corresponding 1-substituted indoles in good to high yields. Similar treatment of the anilines with N-benzyldiethanolamine or triisopropanolamine in place of triethanolamine also affords the indoles in good yields. An intermolecular alkyl group transfer between anilines and alkanolamines is assumed to be the key step of these reactions.

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References

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