The effect of Cultivated Environments on the Antioxidant Enzyme Activities of Codonopsis lanceolata

생육환경이 더덕(Codonopsis lanceolata)의 향산화효소 활성에 미치는 영향

  • Published : 1996.12.01

Abstract

The activities of the antioxidative enzymes in the roots of Codonopsis lanceolata have been compared depending on the cultivated environments - wildness, cultivate paddy fields and cultivate dry fields - and the parts of the root. In the Codonopsis lanceolata raised in cultivate paddy fields, the activity of SOD was higher in 2 yrs old than 1 yr old, but the activity in 1 yr old was higher than in 2 yrs old for the plants raised in the cultivate dry fields. The specific activity of SOD in wildness plants 86.069unit/mg protein was the highest among plants studied. The tissue distribution of the SOD activity showed differences depending on the enviroment. The highest activity of SOD was shown in the upper part of the root for the cultivate paddy fields, the loewr parts for the cultivate dry fields and middle parts for the wildness. The specific activity of POD was increased with ages of the plants, and that in the wildness was the highest 68 unit/mg protein among the plants studied. The activity of POD in the parts of the roots was shown as middle>lower>upper. The activity of POD in the middle part of the root, rasied in Soebick province was 85 unit/mg protein. The specific activity of CAT was decreased with ages of the plants. The activities of wildness and cultivate paddy fields was similar, but that in cultivate dry fields was lower than others. The tissue distribution in the parts of the roots was upper>lower>middle. The activity of CAT middle part of rasied in the Sebuck area was 5.359 unit/mg protein. The activities antioxidative in the cells cultured in MSID(Murashige and Skoog +2.4-D 1mg/$\iota$) was followings: 1564 for CAT. 30 for POD and 22200 unit/mg protein for SOD. These figures were lower than that in in vivo.

더덕 뿌리 내에 함유되어 있는 항산화효소를 생육환경에 따라 조사하기 위하여 경북 서벽지역의 1 2년생 밭더덕, 야생더덕 및 논에서 재배되는 1 2년생 더덕을 채취하여 사용하였고, 부위별 비교는 각 더덕 뿌리를 upper, middle, low로 나누어서 사용하였다. 이들을 O radical caseade인 SOD, POD, CAT activity를 조사하여 다음과 같은 결과를 얻었다. 1. SOD 활성은 밭재배조건의 경우 1년생보다는 2년생이, 논재배시는 1년생이 2년생보다는 높은 활성을 나타내었으며, 야생종의 비활성이 96069u/mg protein으로 가장 높은 활성을 나타내었다. 부위별로 비교해보면 재배종은 upper>middle>lower 순으로 논재배시는 low>upper>middle 순으로 야생종은 middle>lower, upper 순으로 생육환경에 따라 차이를 나타내었다. 2. POD 비활성(u/mg protein)은 년근수가 높을수록 활성은 증가하며, 야생지역이 68 u/mg protein로 가장 높은 활성을 나타내었다. 부위별로는 middle>lower>upper 순으로 활성이 나타났으며, 서벽야생의 middle 부분이 85 u/mg protein를 나타내었다. 3. CAT 활성은 POD 활성과는 달리 년근수가 낮을수록 높게 나타났으며 밭재배지와 야생지의 활성은 비슷하며 논재배지는 상대적으로 그 활성이 낮았다. 부위별로는 upper>low>middle 순으로 upper 부위가 상당히 높은 활성을 나타내며, 서벽재배 1년생의 upper가 53.59 u/mg protein으로 가장 높게 나타났다. 4. MS1D(MS+2.4-D 1ppm)에 배양한 배양세포의 항산화효소의 활성은 CAT는 1564, POD는 30, SOD는 22200 u/mg protein로 생체에 비해 낮은 활성을 나타내었다.

Keywords

References

  1. Methods Enzymol. v.105 Catalase in vitro Aebi,H.
  2. Antioxiants in Higher Plants Alscher,R.G.;Hess,J.L.
  3. Physiol Plants v.85 Ascorbate Peroxidase - a Hydrogen peroxide Seavenging Enzymen in Plants Asada,K.
  4. CRC Critical Reviews in Biochemistry v.22 Aspects of the structure, finction and applications of superxide dismutase Bannishter,J.V.;Bannister,W.H.;Rotilio,G.
  5. Anal. Biochem. v.72 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding Bradford,M.M.
  6. Direct oxidases and related enzymes v.2 In The Biochemistry of Plants Butt,V.S.
  7. Biochemical, Molecular, and physiological Aspects of plant peroxidases Peorxidases in plant growth, diffenentiation, and development processes Gaspar,T.;Penel,C.;Hagege,D.;Greppin,H.;J.Lobarzewski(ed.);H.Greppin(ed.);C.Penel(ed.);T.Gaspar(ed.)
  8. J. Immunoassay v.8 Peroxidase - labelled monoclonal antibodies for use in enzyme - immunoassay Henning,D.;Nielsen,K.
  9. 식물조직배양학회지 v.23 다양한 식물배양세포주에서 catalase 활성과 다른 항산화효소 활성의 비교 장문석;허경혜;김석원;박일현;유장렬;곽상수
  10. 한국생화학회지 v.27 Peroxidase 고생산 식물세포주의 선발 김수경;곽상수;정경희;민성란;박일현;유장렬
  11. 한국농화학회지 v.34 식물의 냉해에 대한 생체방어기구로서 항산화 효소의 유도 : (1) 저온처리중 pyruvate의 세포내 축적과 상온 환원후 항산소성 효소의 활성 김종평;한창균;정진
  12. 한국농화학회지 v.34 식물의 냉해에 대한 생체방어기구로서 항산화 효소의 유도 : (2) Mn +2이온에 의한 세포내 SOD의 활성화와 벼유묘의 내냉성 향상 김종평;한창균;정진
  13. J. Appl. Biochem. v.2 Enzymatic removal of toxic phenols and anilines from waste waters Klibonov,A.H.;Albert,B.N.;Norries,E.D.;Felshin,L.M.
  14. Melecular, and physiology Aspects of plant peroxidase Peroxidase : an important enzyme for diagnostic test kits Krell,H.W.;Lobarzewski,J.(ed.);Greppin,H.(ed.);Penel,C.(ed.);Gaspar,T.(ed.)
  15. 한국 동식물도감 식물편(유용식물) v.15 이덕봉
  16. Plant Physiol. v.110 Overexpression of Copper/Zinc Superoxide Dismutase in the cytosol of Transgenic Tobacco Confers Partial Resistance to Ozone - Induced Foliar Necrosis Lynne H. Pitcher;Barbara A. Zilinskas
  17. Korean J. Food Sci. Technol. v.23 더덕 에탄올 추출물의 항산화효과 맹연선;박혜경
  18. J. Biol. Chem. v.244 Supreoxide dismutase. An enzyme function for erythrocuprein (Hemocuprein) McCord,J.M.;Fridovich,I.
  19. Physiol. Plant. v.15 A revised medium for rapid growth and bioassays with tobacco tissue cultures Murashige,T.;Skoog,F.
  20. 한국농화학회지 v.38 Brassica 속 작물 유묘에서 저온처리에 따른 생화학적 변화 남민희;박무철;박경배
  21. SOD and Active Oxygen Modulators : pharmacology and clinical trials Oyanagui,Y.
  22. Oxygen Radicals in Biological systems : Oxygen Radicals and Antioxidants Parker,L.;Glazer,A.N.
  23. Plants Physiol. v.108 Localization and Characterization of Peroxidases in the Mitochodria of Chilling Acclimated Maize Seedlings Tottenpudi K. Prasad;Nare D. Anderson;Cecil R. Stewart
  24. Proc. Natl. Acad. Sci. USA. v.87 Characterization of iron superoxide dismutase cDNAs from plants obtained by genetic complementation in Escherichia coli Win Van Camp;Chris Bowler;Raimundo Villarroel;W.T.Tsang(ed.);Marc Van Montagu(ed.);Dirk Inze(ed.)
  25. 식물조직배양학회지 v.23 Superoxide dismutase 고생산식물배양 세포주의 선발 및 Isoenzyme 분석 유순희;김석원;김상호;유장렬;곽상수